TAILIEUCHUNG - Báo cáo sinh học: " Effects of pedigree errors on the efficiency of conservation decisions"

Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học quốc tế đề tài: Effects of pedigree errors on the efficiency of conservation decisions | Genetics Selection Evolution BioMed Central Research Effects of pedigree errors on the efficiency of conservation decisions Pieter A Oliehoek and Piter Bijma Address Animal Breeding and Genomic Centre Wageningen University Wageningen Gelderland the Netherlands Email Pieter A Oliehoek - gse@ Piter Bijma - Corresponding author Open Access Published 14 January 2009 Received 22 December 2008 Genetics Selection Evolution 2009 41 9 doi 1297-9686-41-9 Accepted 14 January 2009 This article is available from http content 41 1 9 2009 Oliehoek and Bijma licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Conservation schemes often aim at increasing genetic diversity by minimizing kinship and the best method to achieve this goal when pedigree data is available is to apply optimal contributions. Optimal contributions calculate contributions per animal so that the weighted average mean kinship among candidate parents is minimized. This approach assumes that pedigree data is correct and complete. However in practice pedigrees often contain errors parents are recorded incorrectly or even missing. We used simulations to investigate the effect of these two types of errors on minimizing kinship. Our findings show that a low percentage of wrong parent information reduces the effect of optimal contributions. When the percentage of wrong parent information is above 15 the population structure and type of errors should be taken into account before applying optimal contributions. Optimal contributions based on pedigrees with missing parent information hampers conservation of genetic diversity however missing parent information can be corrected. It is crucial to know which .

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