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The prototypical catalytic reductiveC–Cbond formations, the Fischer-Tropsch reaction [1] and alkene hydroformylation [2], were discovered in 1922 and 1938, respectively [3,4]. These processes, which involve reductive coupling to carbon monoxide, have long been applied to the industrial manufacture of commodity chemicals [5]. Notably, alkene hydroformylation, also known as the oxo-synthesis, has emerged as the largest volume application of homogeneous metal catalysis, accounting for the production of over 7 million metric tons of aldehyde annually. Despite the impact of these prototypical reductive C–C bond formations, this field of research lay fallow for several decades. Eventually, the increased availability of mild terminal reductants, in particular silanes, led to a renaissance in the. | 279 Topics in Current Chemistry Editorial Board V. Balzani A. de Meijere K. N. Houk H. Kessler . Lehn S. V. Ley S. L. Schreiber J. Thiem B. M. Trost F. Vogtle H. Yamamoto Topics in Current Chemistry Recently Published and Forthcoming Volumes Photochemistry and Photophysics of Coordination Compounds II Volume Editors Balzani C. Campagna S. Vol. 281 2007 Photochemistry and Photophysics of Coordination Compounds I Volume Editors Balzani C. Campagna S. Vol. 280 2007 Metal Catalyzed Reductive C-C Bond Formation A Departure from Preformed Organometallic Reagents Volume Editor Krische M. J. Vol. 279 2007 Combinatorial Chemistry on Solid Supports Volume Editor Brase S. Vol. 278 2007 Creative Chemical Sensor Systems Volume Editor Schrader T. Vol. 277 2007 In situ NMR Methods in Catalysis Volume Editors Bargon J. Kuhn L. T. Vol. 276 2007 Sulfur-Mediated Rearrangements II Volume Editor Schaumann E. Vol. 275 2007 Sulfur-Mediated Rearrangements I Volume Editor Schaumann E. Vol. 274 2007 Bioactive Conformation II Volume Editor Peters T. Vol. 273 2007 Bioactive Conformation I Volume Editor Peters T. Vol. 272 2007 Biomineralization II Mineralization Using Synthetic Polymers and Templates Volume Editor Naka K. Vol. 271 2007 Biomineralization I Crystallization and Self-Organization Process Volume Editor Naka K. Vol. 270 2007 Novel Optical Resolution Technologies Volume Editors Sakai K. Hirayama N. Tamura R. Vol. 269 2007 Atomistic Approaches in Modern Biology From Quantum Chemistry to Molecular Simulations Volume Editor Reiher M. Vol. 268 2006 Glycopeptides and Glycoproteins Synthesis Structure and Application Volume Editor Wittmann V. Vol. 267 2006 Microwave Methods in Organic Synthesis Volume Editors Larhed M. Olofsson K. Vol. 266 2006 Supramolecular Chirality Volume Editors Crego-Calama M. Reinhoudt D. N. Vol. 265 2006 Metal Catalyzed Reductive C-C Bond Formation A Departure from Preformed Organometallic Reagents Volume Editor Michael J. Krische With contributions by B. Breit

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