TAILIEUCHUNG - Báo cáo khoa học: Roles of heat shock factors in gametogenesis and development

Heat shock factors form a family of transcription factors (four in mam-mals), which were named according to the first discovery of their activation by heat shock. As a result of the universality and robustness of their response to heat shock, the stress-dependent activation of heat shock factor became a ‘paradigm’: by binding to conserved DNA sequences (heat shock elements), heat shock factors trigger the expression of genes encoding heat shock proteins that function as molecular chaperones | ễFEBS Journal MINIREVIEW Roles of heat shock factors in gametogenesis and development Ryma Abane1 2 and Valerie Mezger1 2 1 CNRS UMR7216 Epigenetics and Cell Fate Paris France 2 University Paris Diderot Paris France Keywords development gametogenesis heat shock mammals transcription factor Correspondence Valerie Mezger CNRS UMR7216 Epigenetics and Cell Fate University Paris Diderot 35 rue Hélène Brion Box 7042 F75013 Paris France Fax 33 1 57 27 89 11 Tel 33 1 57 27 89 14 E-mail Received 10 May 2010 revised 16 July 2010 accepted 23 August 2010 doi Heat shock factors form a family of transcription factors four in mammals which were named according to the first discovery of their activation by heat shock. As a result of the universality and robustness of their response to heat shock the stress-dependent activation of heat shock factor became a paradigm by binding to conserved DNA sequences heat shock elements heat shock factors trigger the expression of genes encoding heat shock proteins that function as molecular chaperones contributing to establish a cytoprotective state to various proteotoxic stress and in several pathological conditions. Besides their roles in the stress response heat shock factors perform crucial roles during gametogenesis and development in physiological conditions. First during these process in stress conditions they are either proactive for survival or conversely for apoptotic process allowing elimination or inversely protection of certain cell populations in a way that prevents the formation of damaged gametes and secure future reproductive success. Second heat shock factors display subtle interplay in a tissue- and stage-specific manner in regulating very specific sets of heat shock genes but also many other genes encoding growth factors or involved in cytoskeletal dynamics. Third they act not only by their classical transcription factor activities but are necessary for .

• Báo cáo khoa học
• Scientific reports
• scientific research
• biochemistry
• biochemical studies
• environmental medicine
• Crystal structure
• collection of scientific reports
• industry reports philosophy of history reports
• reports in literature
• a scientific b shirt
• presentation of scientific reports
• reports on literature
• philosophy statement
• documents
• studies English language and English language communication and English language commercial
• progress reports at scientific collections
• agronomic reports
• reports in physics
• biology reports
• thematic biological
• induced geometry
• mathematical topics
• quantum mechanics
• physics
• reporting mathematics
• physics reports
• livestock reports
• physical reports
• research physicist
• specializing in physics
• mathematical statements
• mathematical equations
• English pronunciation
• presentation report
• agricultural reports
• technical crops
• bio technology
• English reports
• presentation reports
• mathematical knowledge
• reports of mathematics
• represented
• Wilf on packing distinct
• Tur´n density
• mathematical works
• patterns in a permutation
• statements and documents scientific reports
• reports agronomy
• biotechnology
• plants Vietnam
• specialized biological
• microbiological methods
• presenting the report
• anti bacterial properties of shrimp
• energy exchange
• engineering chicken
• Path counting
• random matrix theory
• Even circuits
• prescribed clockwise parity
• Correspondence between
• algorithmic characterizations
• Finding Induced Acyclic
• Random Digraphs
• Nonexistence results
• Hadamard like matrices
• Voltage Graphs
• Group Presentations
• Cages mathematical knowledge
• Dominance Order
• Graphical Partitions
• On the functions
• values in [α(G
• Box With Translates
• Two Given Rectangular Brick
• On the q analogue
• the sum of cubes