TAILIEUCHUNG - The Early Detection Research Network: Investing in Translational Research on Biomarkers of Early Cancer and Cancer Risk

Luigi Grassi MD is Professor and Chair of Psychiatry, Department of Medical Sciences of Communication and Behaviour, University of Ferrara, Italy; and Chief of the Clinical Psychiatry Unit, Department of Neurosciences and Rehabilitation and Department of Mental Heath, S. Anna University Hospital and Local Health Agency in Ferrara, Italy. His research and teaching are mainly in clinical psychiatry, consultation-liaison psychiatry and psycho- oncology. Dr Grassi is the author of several scientific papers and books. He is President of the International Psycho-Oncology Society (IPOS) and the Italian Society of Psycho-Oncology (SIPO) and Chair of the Section on Psycho-Oncology of the World Psychiatric Association (WPA). . | National Cancer Institute Division of Cancer Prevention The Early Detection Research Network Investing in Translational Research on Biomarkers of Early Cancer and Cancer Risk FOURTH REPORT JANUARY 2008 . DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Contents 5 Foreword 7 Introduction 8 Executive Summary Part I Progress and Disease-Specific Developments 14 Chapter 1 Overview 26 Chapter 2 Breast and Gynecologic Cancers 34 Chapter 3 Colorectal and Other Gastrointestinal Cancers 47 Chapter 4 Lung and Upper Aerodigestive Cancers 56 Chapter 5 Prostate and Other Urologic Cancers Part II Process and Collaboration 66 Chapter 6 Validation Stages and Processes 77 Chapter 7 Enabling Technologies Part III Investing in Biomarker Research 91 Chapter 8 Business Model 99 Chapter 9 Evaluating Biomarker Progress in Translational Research 104 Chapter 10 Investing in Biomarker Research for Early Detection Appendix 115 I. Key Publications by Investigators 123 II. Publications Co-Authored by NCI Program Staff 124 Glossary

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