TAILIEUCHUNG - Chapter 084. Head and Neck Cancer (Part 1)

Harrison's Internal Medicine Chapter 84. Head and Neck Cancer Head and Neck Cancer: Introduction Epithelial carcinomas of the head and neck arise from the mucosal surfaces in the head and neck area and typically are squamous cell in origin. This category includes tumors of the paranasal sinuses, the oral cavity, and the nasopharynx, oropharynx, hypopharynx, and larynx. Tumors of the salivary glands differ from the more common carcinomas of the head and neck in etiology, histopathology, clinical presentation, and therapy. Thyroid malignancies are described in Chap. 335. Incidence and Epidemiology The number of new cases of head and neck cancers in. | Chapter 084. Head and Neck Cancer Part 1 Harrison s Internal Medicine Chapter 84. Head and Neck Cancer Head and Neck Cancer Introduction Epithelial carcinomas of the head and neck arise from the mucosal surfaces in the head and neck area and typically are squamous cell in origin. This category includes tumors of the paranasal sinuses the oral cavity and the nasopharynx oropharynx hypopharynx and larynx. Tumors of the salivary glands differ from the more common carcinomas of the head and neck in etiology histopathology clinical presentation and therapy. Thyroid malignancies are described in Chap. 335. Incidence and Epidemiology The number of new cases of head and neck cancers in the United States was 40 500 in 2006 accounting for about 3 of adult malignancies. The worldwide incidence exceeds half a million cases annually. In North America and Europe the tumors usually arise from the oral cavity oropharynx or larynx whereas nasopharyngeal cancer is more common in the Mediterranean countries and in the Far East. Etiology and Genetics Alcohol and tobacco use are the most common risk factors for head and neck cancer in the United States. Smokeless tobacco is an etiologic agent for oral cancers. Other potential carcinogens include marijuana and occupational exposures such as nickel refining exposure to textile fibers and woodworking. Dietary factors may contribute. The incidence of head and neck cancer is highest in people with the lowest consumption of fruits and vegetables. Certain vitamins including carotenoids may be protective if included in a balanced diet. Supplements of retinoids such as m-retinoic acid have not been shown to prevent head and neck cancers or lung cancer and may increase the risk in active smokers. Some head and neck cancers may have a viral etiology. The DNA of human papillomavirus HPV has been detected in the tissue of oral and tonsil cancers and may predispose to oral and tonsillar cancer in the absence of tobacco and alcohol use. These .

• Y học thường thức
• Head and Neck Cancer
• bệnh học và điều trị
• bài giảng bệnh học
• tài liệu y khoa
• Harrisons Internal Medicine
• BMC Cancer
• Head and neck squamous cell carcinoma
• Immune checkpoint inhibitors
• Survival in head and neck cancer
• Alcohol consumption
• Cigarette smoking
• Cohort studies
• Head neck cancer
• Head neck cancer subtypes
• Progressive resistance training
• Physical activity
• Body composition
• Clinical cohort
• Prognosis research
• Patient reported outcomes
• Sexual history
• Quality of life
• Biological samples
• Cell Line Microarray
• Potential immunohistochemical biomarkers
• Triple treatment combination
• Immunotherapy targeting
• Metastatic head
• Neck squamous cell carcinoma
• Cancer stem cells
• Side population
• Delayed neck metastasis
• Inflammatory marker
• Systemic inflammation
• Nonstandard treatment
• Patient compliance
• Cumulative incidence
• Esophageal cancer
• Metachronous cancer
• Young onset
• Head and neck
• Phase III
• Squamous cell carcinoma
• Overall survival
• Platinum therapy
• Narrow band imaging
• Second primary cancer
• Radiation dermatitis
• Topical steroid
• Neck cancer
• Patient derived xenograft
• Squamous cell cancer
• Anti cancer therapeutics
• Warburg effect
• Alternative splicing
• Pyruvate Kinase muscle isoenzyme
• Cancer cells
• Single nucleotide polymorphism
• Personalized medicine
• 5 lipoxygenase
• Representative endocannabinoids
• Effectively inhibited
• Treatment outcome
• Induction chemotherapy
• Neck squamous cells carcinomas
• Metabolic statuses
• CUP syndrome
• Delayed adjuvant therapy
• Advanced head and neck cancer
• Neck dissection
• Human papillomavirus
• Oropharyngeal cancer
• Laryngeal cancer
• Oral cancer
• Chemo radiotherapy exhibiting weak
• Locoregional cancer
• Aspiration pneumonia
• Risk factors
• Cancer related mortality
• Tumor growth
• Meta analysis
• Cancer worldwide
• Anti CD44 v6 antibody
• Antineoplastic treatment
• Indicating greater difficulties
• Circulating tumor cell
• Circulating tumor DNA
• Oral cavity cancer preclinical model