TAILIEUCHUNG - Báo cáo y học: "Epidemiological manifestations of hepatitis C virus genotypes and its association with potential risk factors among Libyan patients"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Epidemiological manifestations of hepatitis C virus genotypes and its association with potential risk factors among Libyan patients | Elasifer et al. Virology Journal 2010 7 317 http content 7 1 317 VIROLOGY JOURNAL RESEARCH Open Access Epidemiological manifestations of hepatitis C virus genotypes and its association with potential risk factors among Libyan patients Hana A Elasifer Yossif M Agnnyia Basher A Al-Alagi Mohamed A Daw Abstract Background The information on hepatitis C virus genotypes and subtypes among Libyan population and its association with various risk factors is not known. The objectives of this study were to determine the epidemiological manifestations of HCV genotypes among Libyan patients and their association with certain potential risk factors. Methods A total of 1240 of HCV infected patients registered at Tripoli Medical Centre were studied in five years period from January 2005 to October 2009. The information were reviewed and the data were collected. A sample from each patient 785 male 455 female was analysed for genotyping and sub-typing using specific genotyping assay. The information was correlated with the risk factors studied and the statistical data were analyzed using SPSS version . Results Off the total patients studied four different genotypes were reported including genotypes 1 2 3 and 4. Genotype4 was the commonest followed by genotype1 . According to subtypes 28 were unclassified genotype 4 were genotype 1b and some patients infected with more than one subtype genotype 4c d 1 genotype 2a c . Genotypes 1 was the commonest among males while genotype 4 among females. According to the risk factors studied Genotype1 and genotype 4 were found with most of the risk factors. Though they were particularly evident surgical intervention dental procedures and blood transfusion while genotype 1 was only followed by genotype 3 mainly which mainly associated with certain risk groups such as intravenous drug abusers. Conclusion Here in we report on a detailed description of HCV genotype among Libyans. The most common genotype was .

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