TAILIEUCHUNG - Chapter 018. Fever and Rash (Part 2)

Centrally Distributed Maculopapular Eruptions Centrally distributed rashes, in which lesions are primarily truncal, are the most common type of eruption. The rash of rubeola (measles) starts at the hairline 2–3 days into the illness and moves down the body, sparing the palms and soles (Chap. 185). It begins as discrete erythematous lesions, which become confluent as the rash spreads. Koplik's spots (1- to 2-mm white or bluish lesions with an erythematous halo on the buccal mucosa) are pathognomonic for measles and are generally seen during the first 2 days of symptoms. They should not be confused with Fordyce's spots (ectopic. | Chapter 018. Fever and Rash Part 2 Centrally Distributed Maculopapular Eruptions Centrally distributed rashes in which lesions are primarily truncal are the most common type of eruption. The rash of rubeola measles starts at the hairline 2-3 days into the illness and moves down the body sparing the palms and soles Chap. 185 . It begins as discrete erythematous lesions which become confluent as the rash spreads. Koplik s spots 1- to 2-mm white or bluish lesions with an erythematous halo on the buccal mucosa are pathognomonic for measles and are generally seen during the first 2 days of symptoms. They should not be confused with Fordyce s spots ectopic sebaceous glands which have no erythematous halos and are found in the mouth of healthy individuals. Koplik s spots may briefly overlap with the measles exanthem. Rubella German measles also spreads from the hairline downward unlike that of measles however the rash of rubella tends to clear from originally affected areas as it migrates and it may be pruritic Chap. 186 . Forchheimer spots palatal petechiae may develop but are nonspecific since they also develop in mononucleosis Chap. 174 and scarlet fever Chap. 130 . Postauricular and suboccipital adenopathy and arthritis are common among adults with German measles. Exposure of pregnant women to ill individuals should be avoided as rubella causes severe congenital abnormalities. Numerous strains of enteroviruses Chap. 184 primarily echoviruses and coxsackieviruses cause nonspecific syndromes of fever and eruptions that may mimic rubella or measles. Patients with infectious mononucleosis caused by Epstein-Barr virus Chap. 174 or with primary infection caused by HIV Chap. 182 may exhibit pharyngitis lymphadenopathy and a nonspecific maculopapular exanthem. The rash of erythema infectiosum fifth disease which is caused by human parvovirus B19 primarily affects children 3-12 years old it develops after fever has resolved as a bright blanchable erythema on the cheeks slapped

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