TAILIEUCHUNG - Pharmaceutical Substances Syntheses, Patents, Applications - Part 177

Pharmaceutical Substances Syntheses, Patents, Applications - Part 177. Reference containing a collection of 2267 active pharmaceutical ingredients, including those launched recently. Listed alphabetically according to their INNs and established a link between INNs, structure, synthesis and production processes, patent and literature situation, medical use, and trade names. For pharmacists and researchers. | Pyrovalerone P 1761 Enbol Merck-Chugai Neurotin Nakataki Neuroxin Yamanouchi Piritiomin Hishiyama Pyrovalerone ATC N06BA Use central stimulant RN 3563-49-3 MF C16H23NO MW CN 1 - 4-methylphcnyl -2- 1 -py rrolidinyl -1 -pentanone hydrochloride _ RN 1147-62-2 MF C16H23NO HC1 MW EINECS 214-556-9 LD50 43 mg kg M . 350 mg kg M . 47 mg kg R . 620 mg kg R . 4 -methylvolerophenone 2-bromo-4 -methyl- volerophenone pyrrolidine Reference s GB 933 507 Thomae appl. D-prior. . GB 927 475 Dr. A. Wander appl. CH-prior. . Formulation s cps. 20 mg Trade Name s F Thymergix Joullié wfm Pyrrobutamine ATC R06AX08 Use antihistaminic RN 91-82-7 MF C2UH22C1N MW EINECS 202-101-7 CN 1 - 4- 4-chlorophenyl -3-phenyl-2-butenyl pyrrolidine phosphate 1 2 RN 135-31-9 MF C2OH22C1N 2H3O4P MW EINECS 205-185-3 LD50 54 mg kg M . 1116 mg kg M . acetophenone poroform-oldehyde pyrrolidine 3-pyrrolidino-propiophenone I 1762 P Pyrrocaine MqCl Cl Pyrrobutomine 4-chlorobenzyl-mognesium chloride Reference s US 2 655 509 Eli Lilly 1953 prior. 1951 . Formulation s labl. 15 mg Trade Name s D Copyronilum Lilly - comb. wfm GB Co-Pyronil Lilly -comb. wfm USA Co-Pyronil Dista -comb. wfm Co-Pyronil Lilly -comb. wfm Pyrrocaine ATC noibb Use local anesthetic RN 2210-77-7 MF C14H20N2O MW CN 7V- 2 6-dimethylphenyl -1 -pyrrolidineacetamide monohydrochloride RN 2210-64-2 MF C14H20N2O HC1 MW EINECS 218-642-7 0 CI -ACI 2 6-dimethyl-aniline NaO CO CHj H20 a-chloro-2 6-dimethylacetonilide chloroocetyl chloride ---------- pyrrolidine Referertce s Lofgren N. et al. Acta Chem. Scand. ACHSE7 11 1724 1957 . Forinidation s vial 2 Trade Name s USA Dynacaine Graham wfm Endocaine Endo wfm Pyrrolnitrin ATC D01AA07 Use antibiotic antifungal RN 1018-71-9 MF C 0H6Cl2N2O2 MW EINECS 213-812-7 LD50 1 g kg M . 2 g kg R . CN 3-chloro-4- 3-chloro-2-nitrophenyl -1 H-pyrrole Pyrvinium embónate P 1763 diethyl omino- malonate t- .

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