TAILIEUCHUNG - Pharmaceutical Substances Syntheses, Patents, Applications - Part 222

Pharmaceutical Substances Syntheses, Patents, Applications - Part 222. Reference containing a collection of 2267 active pharmaceutical ingredients, including those launched recently. Listed alphabetically according to their INNs and established a link between INNs, structure, synthesis and production processes, patent and literature situation, medical use, and trade names. For pharmacists and researchers. | Zorubicin Z 2211 Zorubicin ATC loidbos Use antineoplastic RN 54083-22-6 MF C34H35N3O10 MW LD5 35 mg kg M route unreported CN 2S-cii -benzoic acid l- 4- 3-amino-2 3 6-trideoxy-a-L-iyxo-hexopyranosyl oxy -l 2 3 4 6 11 -hexahydro-2 5 12-trihydro xy-7-methoxy-6 1 l-dioxo-2-naphthacenyl ethylidene hydrazide monohydrochloride RN 36508-71-1 MF C34H35N3O10 HC1 MW E1NECS 253-076-4 LD5i mg kg M . Reference s DOS 2 327 211 Rhône-Poulenc appl. . Formulation s amp. mg as hydrochloride Trade Name s D Zorubicin R. P. Rhône- Poulenc wfm F Rubidazone Rhône- Poulenc wfm Zotepine ATC N05AK Use neuroleptic RN 26615-21-4 MF C18H18C1NOS MW LD5o mg kg M . 108 mg kg M . mg kg R . 306 mg kg R . mg kg dog . 1 g kg dog . CN 2- 8-chlorodibenzo 6J thiepin-10-yl oxy -lVW-dimethylethanamine 4-chloro-thiophenol 2 -chloro-acetophenone NaOH ---- OH 2. CHjCOOH HCI 2212 Z Zotepine polyphosphoric acid ------------------- 0 8-chlorodibenzo b f Jthiepin- 2- dimethylami-no ethyl chloride 10 l1H -one II NaH ------ Reference s US 3 704 245 Fujisawa J-prior. . DOS 1 907 670 Fujisawa appl. J-prior. . GB 1 247 067 Fujisawa appl. J-prior. . Ueda I. et al. Chem. Pharm. Bull. CPBTAL 26 3058 1978 . Formulation s drg. 25 mg 50 mg 100 mg Trade Name s D Nipolept Rhône-Poulenc Rorer J Lodopin Fujisawa 1982 Intermediates 2279 A abietic acid C20H30O2 514-10-3 see Ecabet sodium acefylline C9H qN4O4 652-37-9 see Acefylline acetaldehyde C2H4O 75-07-0 see L-Alanine cw-Cefprozil Chloral hydrate Fencamfamin Fenfluramine Fluroxene Indometacin Methohexital Mitopodozide Netilmicin Zileuton acetaldehyde dimethyl acetal C4H10O2 534-15-6 see Metolazone acetaldehyde 4-methoxyphenyl hydrazone C9HI2N2O 13815-71-9 see Indometacin acetaldehyde thiosemicarbazone C3H7N3S 2302-95-6 see Sulfainethizole acetamide C2H5NO 60-35-5 see Sulfacetamide acetamidine C2H6N2 143-37-3 see Thiamine .

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