TAILIEUCHUNG - Pharmaceutical Substances Syntheses, Patents, Applications - Part 107

Pharmaceutical Substances Syntheses, Patents, Applications - Part 107. Reference containing a collection of 2267 active pharmaceutical ingredients, including those launched recently. Listed alphabetically according to their INNs and established a link between INNs, structure, synthesis and production processes, patent and literature situation, medical use, and trade names. For pharmacists and researchers | Indanazoline I 1061 Reference s DOS 2 618 152 Marpha appl. F-prior. . US4064 255 Marpha F-prior. . Formulation s tabl. 50 mg Trade Name s F Upstène Fournier wfm Indanazoline ATC R01AA Use vasoconstrictor nasal decongestant RN 40507-78-6 MF C12H15N3 MW LD50 mg kg Mf . mg kg Mm . 233 mg kg Mf . 179 mg kg Mm . CN A- 2 3-dihydro-l -inden-4-yl -4 5-dihydro-l -imidazol-2-amine hydrochloride RN 56601-85-5 MF C12HI5N3 xHCl MW unspecified NH SCN- ----k isothiocyonate 4-amina-indan I 0 S N- 4-indanyl -N - benzoylthiaureo II 1. NoOH 2. I CH3 II ---------------- 2. methyl iodide H3C-O S 3H Hl ---------------- 2. ethylenediamine 1. NaOH 1 -acetyl-2-imidazolidinone 1. P0CI3 2. H20 NaOH k 1. phosphoryl chloride Indanazoline 1062 I Indanorex Reference s May . . ARZNAD 30 1733 1980 . a DOS 2 136 325 Nordmark appl. . US 3 882 229 Nordmark D-prior. . b DOS 2 652 004 BASF appl. . Formitlation s nasal drops mg ml spray mg ml as hydrochloride Trade Name s D Farial RIAM Indanorex ATC A08AB Use appetite depressant RN 16112-96-2 MF CI2H17NO MW CN 2- l -aminopropyl -2 3-dihydro-l 7-inden-2-ol hydrochloride RN 16112-95-1 MF C12H17NO HC1 MW HCN hydroxyindane 2-fndonone hydrogen cyonide fHj H-jC i-CH-j Cl ----------------- trimethylchloro- silane 1 ethylmagnesium bromide CH3OH ------- 1. NaBH4 2. HCI 1. sodium barohydride Reference s DOS 2 422 879 Lab. Logeais appl. F-prior. . alternative synthesis FR 2 322 851 Lab. Logeais appl. . use as appetite depressant DOS 2 336 560 Lab. Logeais appl. F-prior. . Trade Name s F Dietor Logeais wfm Indapamide ATC C03BA11 Use diuretic antihypertensive RN 26807-65-8 MF C16H16C1N3O3S MW E1NECS 248-012-7 CN 3- aminosulfonyl -4-chloro-M 2 3-dihydro-2-methyl-l 7-indol-l-yl benzamide Indecainide I 1063 NoN02 2-methyl-indoline ONZ 2-methyl-1 -nitrosoindoline

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