TAILIEUCHUNG - Pharmaceutical Substances Syntheses, Patents, Applications - Part 104

Pharmaceutical Substances Syntheses, Patents, Applications - Part 104. Reference containing a collection of 2267 active pharmaceutical ingredients, including those launched recently. Listed alphabetically according to their INNs and established a link between INNs, structure, synthesis and production processes, patent and literature situation, medical use, and trade names. For pharmacists and researchers | Hydroxyprogesterone H 1031 CX00H r OH h2so4 ------- ethylene glycol salicylic acid I ethylene oxide Hydroxyethyl salicylate Reference s Kaufmann . Arzneimittel-Synthese Springer Verlag 1953 p. 79. DD 218 616 VEB . Werk Oranienburg appl. . Formulation s cream g 100 g g 100 g gel g 100 g g 100 g ointment g 100 g g 100 g Trade Name s D Dolo-Arthrosonex Brenner-Efeka Kytta-Gel Merck Produkte Lumbinon Lichtenstein Phlogont Salbe Azupharma Traumasenex Brenner-Efeka LAW GB ca. 100 combination I preparations Cremalgin Berk -comb. wfm Dubam Norma -comb. wfm Salonair Salonpas -comb. wfm combination preparations only Baisamo Sifcamina Midy Disalgil Also Lasoreum Crema Bayer Mobilisin Luitpold Salonpas Farmila Sloan balsamo Parke Davis Hydroxyprogesterone ATC G03DA03 Use progestogen RN 68-96-2 MF C2lH 0O MW EINECS 200-699-4 CN 17-hydroxypregn-4-ene-3 20-dione acetate RN 302-23-8 MF C23H32O4 MW EINECS 206-119-6 16-dehydrapregnenolone cf. pregnenolone synthesis 1032 H Hydroxyprogesterone so3h Ọ Ọ _ ïï ÏÏ. h3c 0 CH- 2. Qy O AI OCH CH3 2 3 - .---------------. .------- 2. cyclohexanone aluminum triisopropylate Hydroxyprogesterone acetate acetic anhydride ethisterone phenylsulfinyl q. V. chloride IV Reference s a Ringold . et al. J. Am. Chem. Soc. JACSAT 78 816 1956 . US 2 802 839 Syntex 1957 appl. 1953 MEX-prior. 1953 . b US 4 041 055 Upjohn appl. . alternative syntheses US 2 648 662 Glidden 1953 appl. 1949 . US 2 m 843 Merck Co. 1957 appl. 1954 . US 2 786 857 Merck Co. 1957 appl 1954 prior. 1952 . US 2 813 060 Upjohn 1957 appl. 1955 . US 3 000 883 Upjohn 1961 appl. 1957 . Cutler EA. et al. J. Org. Chem. JOCEAH 24 1629 1959 . Formulation s amp. 250mg ml Hydroxyprogesterone caproate H 1033 Trade Name s F Tocogestan Théramex as 17a-heptanoate -comb. Trophobolène Théramex as heptanoate -comb. GB Proluton Depot Schering as hexanoate USA Prodox Upjohn as acetate wfm Hydroxyprogesterone .

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