TAILIEUCHUNG - Pharmaceutical Substances Syntheses, Patents, Applications - Part 9

Pharmaceutical Substances Syntheses, Patents, Applications - Part 9. Reference containing a collection of 2267 active pharmaceutical ingredients, including those launched recently. Listed alphabetically according to their INNs and established a link between INNs, structure, synthesis and production processes, patent and literature situation, medical use, and trade names. For pharmacists and researchers | Amcinonide A 81 Amcinonide atc do7AC11 H02AB Triamcinolone acetate cyclopentanoide Use topical glucocorticoid RN 51022-69-6 MF C28H35FO7 MW EINECS 256-915-2 LD50 5 g kg M . 2 g kg R . CN llß 16a -21- acetyloxy -16 17- cyclopentylidenebis oxy -9-fluoro-ll-hydroxypregna-l 4-diene-3 20-dione hcio4 OH triamcinolone q- v. cyclopentanone triamcinolone cyclopentanonide I Reference s GB 1 442 925 American Cyanamid USA-prior. . DOS 2 437 847 American Cyanamid appl. USA-prior. . BE 818 929 American Cyanamid appl. USA-prior. . US4 158 055 American Cyanamid USA-prior. . Formulation s cream lotion ointment Trade Name s D Amciderm Hermal Merck 1985 F Penticort Wyeth-Lederle 1980 Penticort Neomycine Wyeth-Lederle -comb. I Amcinil Crosara J Visderm Lederle 1982 USA Cyclocort Fujisawa 1979 Amezinium metilsulfate atc coicaoo Use selective noradrenergic antihypotensive RN 30578-37-1 MF CnH12N3O CH3O4S MW EINECS 250-248-0 LD50 28 mg kg M . 1330 mg kg M . 24 mg kg R . 1410 mg kg R . 60 mg kg dog . 100 mg kg dog . CN 4-amino-6-methoxy-l-phenylpyridazinium methyl sulfate A 82 Amfebutamone chloride RN 51410-15-2 MF CnH12ClN3O MW 2-butyne- mucochloric 1 4-diol acid phenylhydrazine Cl 4-amino-5-chlaro-1 -phenyl-6 l H -pyridazinone 4 5-dichloro- 1 -phenyl-6 1 H -pyridozinone I H2 Raney-Ni or Pd-C pyridazinone Reference s Reicheneder F. et al. . ARZNAD 31 II 1529 1981 . DE 1 912 941 BASF appl. . DOS 2 139 687 BASF appl. . DOS 2 211 662 BASF appl. . DOS 3 114 496 BASF appl. . EP 63 267 BASF appl. D-prior. . precursors DE 2 100 685 BASF appl. . Formulation s amp. 5 mg tabl. 10 frig Trade Name s D Regulton Knoll Supratonin Grünenthal Amfebutamone Bupropion ATC N06AE Use antidepressant RN 34911-55-2 MF C13H18C1NO MW LD50 544 mg kg M . CN -l- 3-chlorophenyl -2- I l-dimethylethyl .

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