TAILIEUCHUNG - Pharmaceutical Substances Syntheses, Patents, Applications - Part 6

Pharmaceutical Substances Syntheses, Patents, Applications - Part 6. Reference containing a collection of 2267 active pharmaceutical ingredients, including those launched recently. Listed alphabetically according to their INNs and established a link between INNs, structure, synthesis and production processes, patent and literature situation, medical use, and trade names. For pharmacists and researchers | Alcuronium chloride A Trade Name s D Delonal Essex Pharma 1985 F Aclosone Schering- Plough GB Modrasone Dominion 1986 I Legederm Schering- Plough 1988 J Almeta Shionogi USA Aclovate Glaxo Wellcome 1986 Alcuronium chloride ATC M03AA01 Use muscle relaxant RN 15180-03-7 MF C44H50Cl2N4O2 MW EINECS 239-229-8 LD50 610 pg kg M . 240 pg kg M . 38500 Pg kg M . 610 pg kg M . 270 pg kg R . 27600 pg kg R . 280 pg kg R . CN l - la 3aS 10a llaß 12aJ4aS 19aa 20ba 21a 22aß 23E 26E -2 3 ll lla 13 14 22 22a-octahydro- 23 26-bis 2-hydroxyethylidene -l 12-di-2-propenyl-10 19a 20b 21 7-1 21 10 12-diethano-dipyrrolo 3 2- 3 2 - l 5 diazocino 3 2 l-jZ 7 6 5-jlZ dicarbazolium dichloride allyl iodide N b -ollyl-heminortoxi-ferine iodide 1 Wieland-Gumlich aldehyde degradation product of strychnine ỈỈ CHjCOONa CHjCOOH IRA-400 Cl farm diallylnortoxiferin diiodide II A 52 Aldosterone Reference s US 3 080 373 Roche F-prior. . Karrer P. et al. Angew. Chem. ANCEAD 70 644 1958 . Formulation s amp. 5 ml 10 ml 1 mg ml inj. sol. 10 rng 2 ml Trade Name s D Alloferin Amp. Roche GB Alloferin Roche wfm F Alloférine Roche wfm J Dialferin Roche USA Alloferin Roche wfm Aldosterone ATC H02AA01 Use mineralocorticoid RN 52-39-1 MF C21H28O5 MW EINECS 200-139-9 CN 11 ß -11 21 -dihydroxy-3 20-dioxopregn-4-en-18-al 21 -O-acetylcorticosterone NOCI pyridine nitrosyl chloride 21 -O-ocetyl-11 -O-nRrosyl-corticosterone I 21-O-acetylaldosterone 18-oxime Reference s Barton . Beaton . J. Am. Chem. Soc. JACSAT 82 2641 1960 . starting material The Merck Index 2513 Rahway 1976 . alternative syntheses US 3 002 972 Ciba appl. CH-prior. . US 3 014 029 Ciba appl. CH-prior. . US 3 049 539 Wisconsin Alumni Res. Found. appl. . Wettstein A. et al. Helv. Chim. Acta HCACAV 44 502 1961 . Reichstein T. et al. Helv. Chim. Acta HCACAV 38 1432 1957 . review Fieser . Fieser M. Steroide p. 766 ff .

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