TAILIEUCHUNG - Pharmaceutical Substances Syntheses, Patents, Applications - Part 46

Pharmaceutical Substances Syntheses, Patents, Applications - Part 46. Reference containing a collection of 2267 active pharmaceutical ingredients, including those launched recently. Listed alphabetically according to their INNs and established a link between INNs, structure, synthesis and production processes, patent and literature situation, medical use, and trade names. For pharmacists and researchers | Chlortetracycline C 451 t USA Combipres Boehringer Hygroton Rhône-Poulenc Tenoretic Zeneca Ing. Rorer Thalitone Monarch Chlortetracycline atc aoiab21 DO6AAO2 joiaao3 S01AA02 Use antibiotic RN 57-62-5 MF C22H23C1N2O8 MW EINECS 200-341-7 LD 0 134 mg kg M . 1500 mg kg M . 118 mg kg R . 150 mg kg dog . 750 mg kg dog . CN 4S- 4a 4aa 5aa 6ß 12aa -7-chloro-4- dimethyIamino -1 4 4a 5 5a 6 11 12a-octahydro-3 6 10 12 12a- pentahydroxy-6-methyl-1 11 -dioxo-2-naphthacenecarboxamide monohydrochloride RN 64-72-2 MF C22H23C1N2O8 HCl MW EINECS 200-591-7 LD 0 100 mg kg M . 2314 mg kg M . 100 mg kg R . From fermentation solutions of Streptomyces aureofaciens. Reference s US 2482 055 American Cyanamid 1949 prior. 1948 . US 2 609 329 American Cyanamid 1949 prior. 1948 . US 2 899 422 American Cyanamid 1959 prior. 1956 . US 2 987 449 American Cyanamid prior. . US 3 050 446 American Cyanamid prior. . Duggar . Ann. N. Y. Acad. Sci. ANYAA9 51 175 1948 . Formulations cream 10 mg g 30 mg g 3 eye ointment 10 mg g 1 ointment 30 mg 10 g 3 pastes 30 mg pessaries 100 mg as hydrochloride Trade Name s D Aureodelf Lederle -comb. GB Aureocort Wyeth -comb. Aureomix SlT -comb. Aureomycin Lederle Aureomycin Wyeth J Aureomycin Lederle F Auréomycine Specia Deteclo Wyeth -comb. USA Aureomycin Lederle wfm Tri-antibiotique Chibret Chibret -comb. wfm I Aureocort Cyanamid -comb. Aureomicina Cyanamid wfm 452 C Chlorthenoxazine Chlorthenoxazine ATC N02B Use anti-inflammatory antipyretic analgesic RN 132-89-8 MF C10H10ClNO2 MW EINECS 205-082-3 LD50 g kg M . 10 g kg R . CN 2- 2-chloroethyl -2 3-dihydro-4H-l 3-benzoxazin-4-one 0 salicylamide 1 OHC - 01 3-chloro-propionaldehyde Tos-OH ------ HCI CH3C00H 1 ohc ch2 ------------ Chlorthenoxazine acrolein Reference s a DE 1 021 848 Thomae appl. 1955 . b DE 1 028 999 Thomae appl. 1956 addition to DE 1 021 848 . Formulation s tabl. 200 mg Trade Name s D Cimporhin Tomae .

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