TAILIEUCHUNG - Summary of Biology doctoral thesis: Study on application of gamma Co-60 radiation for production of bioactive water-soluble low molecular weight β-glucan product from spent brewer’s yeast

The objective of the thesis is to successfully build up a process for preparation of bioactive water-soluble low molecular weight β-glucan product from from spent brewer’ yeast by irradiation method. | MYNISTRY OF EDUCATION VIETNAM ACADAMY OF AND TRAINING SCIENCE AND TECHNOLOGY GRADUATE UNIVERSITY SCIENCE AND TECHNOLOGY ----------------------------- Nguyen Thanh Long STUDY ON APPLICATION OF GAMMA Co-60 RADIATION FOR PRODUCTION OF BIOACTIVE WATER-SOLUBLE LOW MOLECULAR WEIGHT β-GLUCAN PRODUCT FROM SPENT BREWER YEAST Major BIOTECHNOLOGY Code 9 42 02 01 SUMMARY OF BIOLOGY DOCTORAL THESIS Ho Chi Minh City - 2020 The thesis was completed at Academy of Science and Technology - Vietnam Academy of Science and Technology. Supervisor 1 Associate Prof. Le Quang Luan Supervisor 2 Associate Prof. Hoang Nghia Son Opponent 1 Opponent 2 Opponent 3 . The thesis is submitted before the Thesis Examination Committee Meeting at Academy of Science and Technology - Vietnam Academy of Science and Technology at time date month year . Thesis can be found at - Library of Academy of Science and Technology - National Library 1 INTRODUCTION The thesis quot Study on application of gamma Co-60 radiation for production of bioactive water-soluble low molecular weight β-glucan product from spent brewer s yeast quot has been carried out at Biotechnology Center of Ho Chi Minh City and Institute of Tropical Biology from November 2015 to May 2019. 1. The urgency of the thesis β-glucan has been widely known as a strongly immune stimulant cholesterol and triglyceride reduction blood sugar regulator wound healing skin rejuvenation etc. β-glucan also has the effect on increasing the number of immune cells and inhibiting the growth of tumors in humans so it has a very strong activity for tumor prevention which help improving the effectiveness of cancer treatment minimizing the side effects from chemical therapy etc. In animal husbandry β-glucan strengthens the immune system and helps animals resisting to some diseases thereby increasing product yield and quality without using antibiotics or stimulant. However β-glucan has a high molecular weight Mw high viscosity and low solubility leads to a poor .

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