TAILIEUCHUNG - Summary of Chemistry doctoral thesis: Study on isolation and investigation of antibiotic and cytotoxic activity of secondary compounds from three actynomycetes strains Streptomyces G246, G261, G248 collected in some central East Vietnam sea

Summary of Chemistry doctoral thesis: Study on isolation and investigation of antibiotic and cytotoxic activity of secondary compounds from three actynomycetes strains Streptomyces G246, G261, G248 collected in some central East Vietnam sea | MINISTRY OF EDUCATION AND VIETNAM ACADEMY TRAINING OF SCIENCE AND TECHNOLOGY GRADUATE UNIVERSITY OF SCIENCE AND TECHNOLOGY ---------------------------- CAO DUC DANH STUDY ON ISOLATION AND INVESTIGATION OF ANTIBIOTIC AND CYTOTOXIC ACTIVITY OF SECONDARY COMPOUNDS FROM THREE ACTINOMYCETES STRAINS STREPTOMYCES G246 G261 G248 COLLECTED IN SOME CENTRAL EAST VIETNAM SEA Major Organic Chemistry Code 9 44 01 14 SUMMARY OF CHEMISTRY DOCTORAL THESIS HA NOI- 2019 This thesis was completed at Graduate University Science and Technology - Vietnam Academy of Science and Technology Advisor 1 Prof. Dr. Habil. Pham Van Cuong Advisor 2 Dr. Tran Dang Thach 1st Reviewer 2nd Reviewer 3rd Reviewer The thesis will be defended at Graduate University of Science and Technology - Vietnam Academy of Science and Technology at hour date month 2019 The thesis can be found in - The library of the Graduate University of Science and Technology Vietnam Academy of Science and Technology. - The National Library of Vietnam. 1 INTRODUCTION 1. The urgency of the thesis The ocean accounts for 70 of the earth s surface where there is the largest biological diversity on earth. It is home to 34 of the 36 animal and plant sectors on earth with more than 300 000 known species. The marine environment has been known as a rich source of natural compounds such as a huge pharmaceutical warehouse awaiting exploration and discovery. Characteristics of harsh deep sea habitats are the conditions for forming organic compounds with unique chemical structure characteristics and precious biological activity. The study of secondary active ingredients produced from marine microorganisms in the world has achieved many remarkable achievements. Among them are many secondary compounds with interesting chemical structure and biological activity. At the same time many of these compounds are being tested further for medical applications. Vietnam is located in the Pacific region with sovereignty with an area of about 1 000 000 km2 .

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