TAILIEUCHUNG - Vitamin E ameliorates the mineralo-oxidative stress of sucking lice infestation in Indian water buffalo

Bubaline pediculosis is a common and economically important ectoparasitic condition caused by sucking lice, Haematopinus tuberculatus. This condition in buffalo is characterized by anemia, mineral imbalance, and loss of production performance but its pathobiology is explored less. Aim of the present study was to explore the mineralooxidaive pathobiology of bubaline pediculosis and its amelioration using the two antioxidants as an adjunct therapeutic modality (N- acetyl cysteine and Vitamin E). Twenty four buffaloes, severely infested with sucking lice (mean total lice count more than 100) were divided into three groups (Group I, II and III) with eight animals per group; another eight animals (Group IV) free from any clinical abnormalities and ectoparasitism were included as healthy control. Lice infested animals (Group I, II and III) animals were given ivermectin therapy (200 µg/kg body weight SC single dose); additionally, group II and group III animals were orally treated with N-acetyl cysteine (12 mg/kg body weight) and vitamin E (Tocopheryl acetate 4000 mg per animal), respectively, once daily for 14 days. The haematological parameters (TEC, Hb, TLC and DLC), oxidant-antioxidant profile (TAC, LPO, GSH, and SOD) and mineral profile (Zinc, Iron, Magnesium, and Copper) were studied on before therapy (Day 0) and post therapy (Day 28). Bubaline pediculosis revealed severe oxidative stress and mineral imbalance along with remarkable anaemia and leukocytosis. Vitamin E given animals demonstrated better recovery from the mineralo-oxidative pathology of bubaline pediculosis and approached post therapeutic normalcy. | Vitamin E ameliorates the mineralo-oxidative stress of sucking lice infestation in Indian water buffalo

TỪ KHÓA LIÊN QUAN
Đã phát hiện trình chặn quảng cáo AdBlock
Trang web này phụ thuộc vào doanh thu từ số lần hiển thị quảng cáo để tồn tại. Vui lòng tắt trình chặn quảng cáo của bạn hoặc tạm dừng tính năng chặn quảng cáo cho trang web này.