TAILIEUCHUNG - Chewing maintains hippocampus-dependent cognitive function

Mastication (chewing) is important not only for food intake, but also for preserving and promoting the general health. Recent studies have showed that mastication helps to maintain cognitive functions in the hippocampus, a central nervous system region vital for spatial memory and learning. | Int. J. Med. Sci. 2015 Vol. 12 502 ivyspring international publisher Review InternationalJournal ofMedicalSciences 2015 12 6 502-509. doi Chewing Maintains Hippocampus-Dependent Cognitive Function Huayue Chen1 Mitsuo linuma2 Minoru Onozuka3 Kin-Ya Kubo4 1. Department of Anatomy Gifu University Graduate School of Medicine Gifu 501-1194 Gifu Japan 2. Department of Pediatric Dentistry Division of Oral Structure Function and Development Asahi University School of Dentistry Mizuho 501-0296 Gifu Japan 3. Department of Judo Therapy and Medical Science Faculty of Medical Science Nippon Sport Science University Yokohama 227-0033 Kanagawa Japan 4. Seijoh University Graduate School of Health Care Studies Tokai 476-8588 Aichi Japan Corresponding author Dr. H. Chen Department of Anatomy Gifu University Graduate School of Medicine 1-1 Yanagido Gifu 501-1194 Gifu Japan. Phone 81 58 230 6295 Fax 81 58 230 6298 Email huayue@. Dr. Kin-ya Kubo Seijoh University Graduate School of Health Care Studies Tokai 476-8588 Aichi Japan. Email kubo@ 2015 Ivyspring International Publisher. Reproduction is permitted for personal noncommercial use provided that the article is in whole unmodified and properly cited. See http terms for terms and conditions. Received Accepted Published Abstract Mastication chewing is important not only for food intake but also for preserving and promoting the general health. Recent studies have showed that mastication helps to maintain cognitive functions in the hippocampus a central nervous system region vital for spatial memory and learning. The purpose of this paper is to review the recent progress of the association between mastication and the hippocampus-dependent cognitive function. There are multiple neural circuits connecting the masticatory organs and the hippocampus. Both animal and human studies indicated that cognitive functioning is influenced by mastication. .

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• Central nervous system
• Spatial memory
• Hippocampus dependent cognitive function
• Masticatory organs
• Dentate gyrus
• The central nervous system
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• Neuropathology of vascular disease
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• Pathology of degenerative diseases
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