TAILIEUCHUNG - Prevalence of hepatopathy in type 1 diabetic children

The Prevalence of liver disease among diabetics has been estimated to be between 17% and 100%. Most of these data were obtained from adult studies. The aim of our study was to screen for liver disease among type 1 diabetic children. | Al-Hussaini et al. BMC Pediatrics 2012 12 160 http 1471-2431 12 160 BMC Pediatrics RESEARCH ARTICLE Open Access Prevalence of hepatopathy in type 1 diabetic children A 1 1 1 1 A A 1 1 1 1 K I A A í- 1 7 A A - A 1 7 1 7 A 1 I A I 7 I A A 1 1 7 Abdulrahman A Al-Hussaini Nimer M Sulaiman2 Musa D AlZahrani Ahmed S Alenizi2 and Mannan Khan3 Abstract Background The Prevalence of liver disease among diabetics has been estimated to be between 17 and 100 . Most of these data were obtained from adult studies. The aim of our study was to screen for liver disease among type 1 diabetic children. Methods Children with type 1 diabetes following in clinic have been examined for existence of liver disease from November 2008 to November 2009. All were subjected to the following History physical examination liver function tests fasting lipid profile HbA1C and ultrasound of the liver. A hyperechogenic liver and or hepatomegaly on ultrasound were attributed most likely to excess glycogen or fat in the liver after negative extensive work-up to rule out other underlying liver disease. Results 106 children with type 1 diabetes were studied age ranged between 8 months to years sixty two patients were females. Twenty two patients 21 were identified to have abnormal findings on ultrasound of the liver 10 patients had hepatomegaly and 12 had hyperechogenic liver. The group with hyperechogenic liver had poorer glycemic control than patients with normal liver Mean HbA1c Vs P value . Hyperechogenic liver resolved in 60 at 6 months follow-up upon achieving better glycemic control. Conclusions Hyperechogenic liver and or hepatomegaly are not uncommon in children with type 1 diabetes and tend to be more prevalent among children with poor glycemic control. Type 1 diabetes related hepatopathy is reversible by optimizing glycemic control. Because of its safety and reliability ultrasound can be used to screen for hepatopathy in type 1 diabetic child. Keywords

• Y khoa - Dược
• BMC Pediatrics
• Fatty liver
• Hepatic glycogenosis
• Type 1 diabetes
• Diabetes mellitus
• Acute otitis media
• Primary care pediatrics
• Pneumatic otoscope
• Educational programmes concerning
• National Institutes of Health
• Pediatric integrative medicine
• Healthcare professionals
• Alternative medicine
• Lumbar puncture
• Early onset neonatal sepsis
• American Academy of Pediatrics
• Group B Streptococcus
• 9 Kids’ Inpatient Database
• Public health
• Tasmanian Law Reform Institute
• Non therapeutic circumcision
• Long QT syndrome
• Standing test
• Pediatric emergency department
• Ventricular arrhythmias
• Acute respiratory infection
• Under five years
• Death especially
• Binary logistic regression analysis
• Pediatrics mortality
• Emergency department
• Tikur Anbessa Specialized Tertiary Hosptal
• Neonatal intensive care unit
• RV infection
• Pediatrics guidelines criteria
• Gynecology hospitals
• Demographic data collection
• Electronic health record
• Health care organizations
• Screen viewing
• Psychological wellbeing
• Moderate to vigorous intensity physical activity
• Child abuse pediatrics
• Social risk indicators
• Non social cues
• CAP risk perception
• Not included in the title
• Quality of health care
• Patient satisfaction
• Emergency medical services
• Isolated unilateral temporalis muscle hypertrophy
• IUTMH in pediatrics
• Masticatory muscle hypertrophies
• Visual disturbances
• Pediatrics antiretroviral market
• Pediatric antiretroviral prices
• Global Price Reporting Mechanism
• Price trends
• Pediatric antiretroviral procurement
• Hospitalized children
• Antimicrobial stewardship
• Prescribing antimicrobials
• Discontinuing empiric antimicrobials
• Pediatric tumors
• Infantile orbital tumors
• Isolated enophthalmos
• Orbital tumors
• Care seeking behavior
• Traditional medicine
• National Hospital of Pediatrics
• Neonatal jaundice
• Transcutaneous bilirubin
• Neonatal hyperbilirubinemia
• Especially kernicterus
• Parental decisions regarding immunization
• Knowledge practices
• Immunization rate
• Knowledge practice
• Factors underlying inadequate
• Unvaccinated children
• Epileptic attack
• School absenteeism
• Childhood epilepsy
• Epilepsy in Ethiopia
• Social media
• Infant care
• Anticipatory guidance
• Preschool teachers
• Knowledge retention
• Pediatric first aid
• Ulcerative colitis
• Inflammatory bowel diseases
• Childhood onset Crohn’s disease
• Histopathological examination
• Intestinal spirochetosis
• Brachyspira aalborgi
• Brachyspira pilosicoli
• Inflammatory bowel disease