TAILIEUCHUNG - Hepatitis C virus infection, and neurological and psychiatric disorders – A review

An association between hepatitis C virus infection and neuropsychiatric symptoms has been proposed for some years. A variety of studies have been undertaken to assess the nature and severity of these symptoms, which range from fatigue and depression to defects in attention and verbal reasoning. There is evidence of mild neurocognitive impairment in some patients with HCV infection, which is not fully attributable to liver dysfunction or psychosocial factors. Further evidence of a biological cerebral effect has arisen from studies using magnetic resonance spectroscopy; metabolic abnormalities correlate with cognitive dysfunction and resemble the patterns of neuroinflammation that have been described in HIV infection. Recent research has suggested that, in common with HIV infection, HCV may cross the blood brain barrier leading to neuroinflammation. Brain microvascular endothelial cells, astrocytes and microglia may be minor replication sites for HCV. Importantly, patient reported outcomes improve following successful antiviral therapy. Further research is required to elucidate the molecular basis for HCV entry and replication in the brain, and to clarify implications and recommendations for treatment. | Hepatitis C virus infection, and neurological and psychiatric disorders – A review

• Y khoa - Dược
• Hepatitis C
• Hepatitis C virus infection
• Neurological and psychiatric disorders
• Magnetic resonance spectroscopy
• HIV infection
• Hepatitis C treatment
• hepatitis treatment
• hepatitis C prevention
• prevention of hepatitis C
• Management of acute viral hepatitis
• Acute hepatitis A
• Acute hepatitis B
• Acute hepatitis C
• Acute hepatitis E
• Hepatitis B surface antigen
• Hepatitis C antibody
• Pre operative patients
• Tertiary care hospital
• Antenatal women
• Hepatitis B
• New born
• Hepatitis C and syphilis
• Hepatitis C viral infections
• Multiple blood transfusions
• Patients undergoing multiple blood
• Diagnosis of Hepatitis
• Hepatitis Basics
• blood screening
• internal organs
• Blood transfusion
• Thalassemic patients
• Hepatology a clinical textbook
• Hepatitis A
• Hepatitis E
• HBV Virology
• BMC Pediatrics
• Hepatitis B virus
• Hepatitis B surface antibody
• Hepatitis C virus
• HBV antigen
• BMC Cancer
• Cancer risk
• Chronic hepatitis infection
• Confidence intervals
• Hepatocellular carcinoma
• Hepatitis D virus
• Direct acting antivirals
• Direct acting antiviral agents
• Treating chronic hepatitis C infection
• Phylogenetic tree
• NS5B based genotyping
• Patients from Damietta governorate
• 50 UTR hepatitis C virus
• Occult hepatitis C infection
• Clinical relevance
• Lymphoproliferative disorders
• HCV infection
• Prevalence of hepatitis C Virus
• Infection in a patients attending
• Liver failure
• Sequence heterogeneity in the core
• NS5A region of hepatitis C Virus
• IL 28B polymorphisms in predicting treatment response
• Chronic HCV genotype 4 infected
• Pilot study of occult hepatitis C virus
• Occult hepatitis C virus
• Egyptian blood donors
• HCV RNA from plasma
• Blood donors according to presence of HCV RNA
• Risk factor
• Pegylated interferon alpha
• Risk factors of depression
• Anxiety in hepatitis C patients
• BMC Musculoskeletal Disorders
• Human immunodeficiency virus
• Chronic HCV monoinfection
• Ascertain joint pain
• Hepatitis C virus genotype 4
• Chronic hepatitis
• Promoter methylation
• Disease progression
• Interferon lambda 3
• Hepatic steatosis
• Chronic hepatitis cirrhosis
• Solid tumors
• HBV screening
• Cardiovascular risk
• Hepatitis C virus and cardiovascular
• Increase cardiovascular risk
• Non Hodgkin lymphoma
• Antiviral treatment
• Non Hodgkin’s lymphomas