TAILIEUCHUNG - The role of YB1 in renal cell carcinoma cell adhesion

Y-box binding protein 1 (YB1) is a multifunctional protein involved in many processes related to cancer progression and metastasis. | Int. J. Med. Sci. 2018 Vol. 15 1304 IVYSPRING ĩvt ơ-rnrt irmrtí clrni t n lí ei-fCMo Tir lT Qriữvtrơc INTERNATIONAL PUBLISHER international journal Oj jVLeaicaiSciences 2018 15 12 1304-1311. doi Research Paper The Role of YB1 in Renal Cell Carcinoma Cell Adhesion Yong Wang1 Jing Su1 Donghe Fu1 2 Yiting Wang1 Yajing Chen3 Ruibing Chen4 Guoxuan Qin5 Jing Zuo1 Dan Yue1 1. Department of Urology The Second Hospital of Tianjin Medical University Tianjin Institute of Urology and Department of Microbiology School of Medical Laboratory Tianjin Medical University Tianjin 300070 China 2. Department of Clinical Laboratory Tianjin Medical University General Hospital Tianjin Medical University Tianjin 300052 China 3. Research Center of Molecular Biology Inner Mongolia Medical University Hohhot 010059 China 4. Department of Genetics School of Basic Medical Sciences Tianjin Medical University Tianjin 300070 China 5. School of Microelectronics Tianjin University Tianjin 300072 China These authors contribute equally to this work. E Corresponding author Dan Yue . Department of Microbiology School of Medical Laboratory Tianjin Medical University Tianjin 300070 China. Email yuedan@ Ivyspring International Publisher. This is an open access article distributed under the terms of the Creative Commons Attribution CC BY-NC license https licenses by-nc . See http terms for full terms and conditions. Received Accepted Published Abstract Background Y-box binding protein 1 YB1 is a multifunctional protein involved in many processes related to cancer progression and metastasis. Methods In this study we constructed YB1 knockdown stable renal cell carcinoma RCC cell line 786-0. The gene expression profile of 786-0 was performed by DNA microarray analysis to identify genes that were regulated by YB1. Real-time PCR and western blotting were used to test the genes and proteins expression. .

• Y khoa - Dược
• Cell adhesion
• Renal cell carcinoma
• Y box binding protein 1
• DNA microarray analysis
• Real time PCR
• Transforming growth factor β
• Cellular adhesion
• Adhesion molecules
• Cell adhesion molecules
• Biological processes
• Including embryonic cell migration
• Immune system functions
• BMC Biotechnology
• Mussel adhesion
• Escherichia coli
• BMC Molecular and Cell Biology
• Ephrin A
• Eph signaling
• Inhibiting cell adhesion
• Macrophage cell lines
• Adhesion molecule
• Cell cell adhesion
• Kidney epithelium
• Epithelial cells
• Pancreatic intraepithelial neoplasia
• Carcinoembryonic antigen
• Related cell adhesion molecules
• Linked immunoglobulin
• BMC Cancer
• AMP activated protein kinase
• Hepatocellular carcinoma
• Intercellular adhesion molecule 1
• Vascular cell adhesion molecule 1
• Polycystin 1
• Focal adhesion turnover
• Focal adhesion kinase
• Renal cysts
• Gene knockdown
• Epithelia mesenchymal transition
• Glucose regulated protein 78
• Pathological cell stress
• Gliomas account
• Glioma malignancy
• L1 adhesion molecule
• Glial tumors
• Actin polymerization
• Substrate adhesion
• Dictyostelium discoideum
• Mound apex
• Carbohydrate polymers
• Cell adhesion inhibition
• Wound regeneration
• Adhesion inhibitor
• Collagen hydrogel
• Multiple myeloma
• Cell adhesion mediated
• Drug resistance
• Integrin β1
• Numbl influences cell cycle
• Epithelial cell adhesion molecule
• Synthesize DNA
• EpCAM positive cells
• CHL cell
• Protein synthesis
• Extracellular matrix
• Neubave hemocytometer
• P13 kinase
• Melanoma cell adhesion
• Anchoring cells
• Initiate intracellular signal pathways
• Mitogen activated protein kinase
• Prostate cancer
• Animal model
• Castration resistant prostate cancer
• Cytostatic concentrations
• Cytoskeletal dynamics
• Metastatic cancer cells
• Cellular morphology
• Membrane associated guanylate kinase
• Scaffold proteins
• E Cadherin
• Moderate morphogenetic
• Cell adhesion molecule L1
• CHO cells
• Cancer cell differentiation
• Mechanism remains unclear
• Sialic acid rich glycoproteins
• Colon cancer
• Tumour suppressor
• Surgical stress
• Perioperative phase
• Von Willebrand factor
• Platelet adhesion
• Shear activation
• Primary haemostasis
• T cell malignancies
• Cell signaling
• Multifunctional membrane protein
• T cell biology
• Aggressive cancers
• Neural stem cell
• Cell cycle
• Gene expression
• Neuropsychiatric disorders
• BMC Veterinary Research
• Campylobacter jejuni
• Lactobacillus spp
• Chicken and pig cell line
• Campylobacter adhesion