TAILIEUCHUNG - Phytosome mangostin from garcinia mangostana

Studies have demonstrated that free radicals (ROS) such as hydrogen peroxide (H2O2), superoxide (O2 - ), hydroxyl radical (OH- ) are the cause of aging in humans. The basis of this phenomenon is that they can cause oxidative damage to cell biological macromolecules such as proteins, lipids or DNA through increasing peroxide oxidation, altering DNA structure. | Research PHYTOSOME MANGOSTIN FROM GARCINIA MANGOSTANA Le Minh Tri Doan Thanh Huyen Ngo Thi Thuy Phuong Abstract Studies have demonstrated that free radicals ROS such as hydrogen peroxide H2O2 superoxide O2 hydroxyl radical OH are the cause of aging in humans. The basis of this phenomenon is that they can cause oxidative damage to cell biological macromolecules such as proteins lipids or DNA through increasing peroxide oxidation altering DNA structure. increasing the amount of carbonyl protein reducing the content of glutathione GSH and inhibiting or losing the activity of cell-protective enzyme systems like superoxide dismutase SOD catalase CAT peroxidase glutathione reductase GR Storz and Imlay 1999 . Keywords Oxidation SOD CAT GSH Liver cancer Lung cancer a-mangostin Y-mangostin. 1. INTRODUCTION Studies have demonstrated that free radicals ROS such as hydrogen peroxide H2O2 superoxide O2- hydroxyl radical OH- are the cause of aging in humans. The basis of this phenomenon is that they can cause oxidative damage to cell biological macromolecules such as proteins lipids or DNA through increasing peroxide oxidation altering DNA structure. increasing the amount of carbonyl protein reducing the content of glutathione GSH and inhibiting or losing the activity of cell-protective enzyme systems such as superoxide dismutase SOD catalase CAT peroxidase glutathione reductase GR Storz and Imlay 1999 . Xanthones including mangostins were found to be able to suppress ROS roots thus having antioxidant effects. This activity of xanthone is even much more powerful than the activity of vitamins C and E which are considered to have strong antioxidant properties Ee et al. 2008 . In vitro studies of Williams et al. Williams et al. 1995a and followed by Mahabusarakam et al Mahabusarakam et al. 2000 have shown that mangostin in mangosteen pods inhibits oxidation. Low density lipoprotein LDL lipoproteins. Here mangostin acts as a free-radical hunter to protect LDLs from oxidative damage

• Hoá dầu
• Phytosome mangostin
• Garcinia mangostana
• Liver cancer
• Lung cancer
• α mangostin
• γ mangostin
• Luận văn Thạc sĩ Khoa học
• Sinh học thực nghiệm
• Khả năng chống oxi hóa
• Hoạt chất mangostin phytosome
• Nuôi cấy vi sinh vật
• Măng cụt
• Ung thư gan
• Ung thư phổi
• Bào chế phytomsome
• Tính thấm của dược chất
• Luận văn Thạc sĩ
• Luận văn Thạc sĩ Sinh học thực nghiệm
• Vi sinh vật gây bệnh ở người
• Khả năng chống oxi hóa ở động vật
• Công nghệ tạo hoạt chất mangostin phytosome