TAILIEUCHUNG - The value of 18FDG PET/CT for initial staging diagnosis of breast cancer

Objectives: To determine the value of 18FDG PET/CT in initial staging diagnosis of breast cancer patients. Subjects and methods: 36 breast cancer patients were performed 18FDG PET/CT for initial staging diagnosis before the treatment. | Journal of military pharmaco-medicine n06-2018 THE VALUE OF 18FDG PET/CT FOR INITIAL STAGING DIAGNOSIS OF BREAST CANCER Nguyen Trong Son*; Nguyen Danh Thanh** SUMMARY Objectives: To determine the value of 18 FDG PET/CT in initial staging diagnosis of breast cancer patients. Subjects and methods: 36 breast cancer patients were performed 18 FDG PET/CT 18 for initial staging diagnosis before the treatment. Results: The FDG PET/CT changed in 6/36 patients () by T stage, in 11/36 patients () by N stage, detected metastasis in 8 18 patients. After FDG PET/CT, 13/36 patients () upstaged diagnosis which included 8/24 18 patients () at stage II and 5/8 patients () at stage III. The FDG PET/CT did not change diagnosis in patients with clinical stage I. Conclusion: 18 FDG PET/CT scan could effectively detect axillary and extra-axillary nodes, distant metastasis with great value in staging diagnosis in breast cancer patients. * Keywords: Breast cancer; 18 FDG-PET/CT; Staging diagnosis. INTRODUCTION Breast cancer is diagnosed based on clinical symptoms, histology and diagnostic imaging. Common diagnostic imaging tools included mammography, ultrasound, computed tomography scan (CT-scan) and lately magnetic resonance imaging (MRI). Early diagnosis of breast cancer in examination periods and screening programs has brought great value in successful treatment. Positron emission tomography/computed tomography with flourine-1818 fluorodeoxyglucose ( FDG PET/CT) allowed early detection of pathological metabolism before changing anatomy and physiology, providing important information for accurate staging and thence, proposing appropriate treatment regimen. The value of 18FDG PET/CT had been demonstrated in accurate diagnosis of tumor location, staging progress of breast cancer, evaluating axillary and extra-axillary lymphatic nodes (upper and lower clavicular nodes, internal mammary nodes). 18FDG PET/CT also works as a significant tool in .

• Y khoa - Dược
• Breast cancer
• Staging diagnosis
• 18FDG PET CT
• Extra axillary nodes
• Computed tomography scan
• Magnetic resonance imaging
• BMC Cancer
• Breast cancer screening
• Familial breast cancer
• Young breast cancer survivors
• High risk relatives
• Randomized trial
• Breast cancer management
• Gross anatomy
• The breast
• Breast cancer epidemiology
• Hereditary breast cancer genetics
• Prediction techniques
• Cancer susceptibility gene
• Breast cancer prognosis
• Next generation sequencing
• Breast specific gamma imaging
• Diagnosing breast cancer during
• Ductal carcinoma in situ
• DNA methylation
• Breast epithelial cells
• Breast cancer campaign tissue bank
• Breast milk
• Axillary lymph node dissection
• Breast cancer related lymphedema
• Breast lymphatics level
• Ovarian cancer
• Mauritanian breast cancer patients
• Triple negative breast cancer
• Molecular subtype
• Cholesterol observed
• Female breast cancer
• Breast feeding
• World Health Organization
• Inflammatory breast cancer
• Case comparison study
• Family history of breast cancer
• Breast cancer risk factors
• Multiplex IBC families
• Carcinoma associated fibroblasts
• Breast cancer pathogenesis
• Breast cancer cell biology
• Cytokine molecules mediating
• Stage IV breast cancer
• Metastatic breast cancer
• Diagnostic marker
• Searching reliable
• Protein cancer biomarkers
• Breast fluid secretome
• breast cancer second edition
• Breast Sonography
• Radionuclide Imaging of the Breast
• Mammography
• Breast Reconstruction
• Chemotherapy for Breast Cancer
• Breast imaging
• Breast pathology
• Breast soft tissue
• Breast cancers
• Breast tumorigenesis
• Non steroidal anti inflammatory drug
• Hormone receptor positive breast cancer
• HER2 positive breast cancer
• Aggressive tumor phenotype
• Health care
• Including increased frequency
• Polygenic risk score
• Single nucleotide polymorphisms
• Artifcial neural network
• Estrogen receptor negative breast cancer
• Mammographic breast density
• Breast cancer risk
• Atypical hyperplasia
• Established risk factors
• Non melanoma skin cancer
• Metastatic cancer
• Reduce ethnic
• Multivariate models adjusting
• Cancer survivorship
• Cancer prevalence
• Statistical projection
• Toll like receptor 4
• +3725G C polymorphism
• Egyptian breast cancer atients
• Breast cancer cases than controls
• Post treatment breast cancer patients
• Pre treatment breast cancer
• Extraaxilary nodes
• Distance metastases
• Breast cancer cell lines
• Breast tumor subtypes
• Topoisomerase I
• Camptothecin sensivity
• Epithelial type
• Triplenegative breast carcinomas
• N terminal p63 isoforms