TAILIEUCHUNG - Synthesis and structural study of some 4 (2 Aylidenehydrazinyl) 7 Chloroquinoline compounds

7-Chloro-4-hydrazinylquinoline and seven hydrazone derivatives were synthesized from 4,7- dichloroquinoline. The structures of the compounds were determined by IR, 1H-NMR, 13C-NMR and HR-MS spectral data. | TRƯỜNG ĐẠI HỌC SƯ PHẠM TP HỒ CHÍ MINH TẠP CHÍ KHOA HỌC HO CHI MINH CITY UNIVERSITY OF EDUCATION JOURNAL OF SCIENCE KHOA HỌC TỰ NHIÊN VÀ CÔNG NGHỆ NATURAL SCIENCES AND TECHNOLOGY ISSN: 1859-3100 Tập 14, Số 3 (2017): 5-11 Vol. 14, No. 3 (2017): 5-11 Email: tapchikhoahoc@; Website: SYNTHESIS AND STRUCTURAL STUDY OF SOME 4-(2-ARYLIDENEHYDRAZINYL)-7-CHLOROQUINOLINE COMPOUNDS Le Trong Duc1, Nguyen Tien Cong1*, Nguyen Quang Tung2 1 Ho Chi Minh City University of Education 2 Hanoi University of Industry Received: 14/02/2017; Revised: 03/3/2017; Accepted: 24/3/2017 ABSTRACT 7-Chloro-4-hydrazinylquinoline and seven hydrazone derivatives were synthesized from 4,7dichloroquinoline. The structures of the compounds were determined by IR, 1 H-NMR, 13C-NMR and HR-MS spectral data Keywords: 4-(2-arylidenehydrazinyl)-7-chloroquinoline, 7-chloro-4-hydrazinylquinoline, 4,7-dichloroquinoline. TÓM TẮT Tổng hợp và xác định cấu trúc một số hợp chất 4-(2-arylidenehydrazinyl)-7-chloroquinoline 7-Chloro-4-hydrazinylquinoline và bảy dẫn xuất dạng hydrazone của nó (trong đó có 3 hợp chất mới) đã được tổng hợp từ 4,7-dichloroquinoline. Cấu trúc của các chất tổng hợp được đã được xác nhận bởi các phổ IR, 1H-NMR, 13C-NMR và phổ khối lượng độ phân giải cao. Từ khóa: 4-(2-arylidenehydrazinyl)-7-chloroquinoline, 7-chloro-4-hydrazinylquinoline, 4,7dichloroquinoline. 1. Introduction Hydrazones containing quinoline heterocycle have been of great interest in medicinal chemistry for their role as anticancer, antibacterial, antifungal, anti-tubercular agents [1-7]. It has been evidenced from literature survey that the bioactivity of these compounds were affected by the presence or absence of chlorine substituent at the 7 th position in quinoline heterocycle as well as the properties of some substituents in molecule of these hydrazones [4,5]. Although synthesis and bioactive of some hydrazones synthesized from 4,7dichloroquinoline were reported, spectral data

• Hoá học
• Synthesis and structural study
• Synthesis and structural
• Chloroquinoline compound and aylidenehydrazinyl
• HRMS spectral data
• The structures of the compounds
• BMC Musculoskeletal Disorders
• Physeal hypertrophic zone
• Structural cell
• Matrix synthesis problem
• Growth plate histomorphometry
• Phương pháp phổ IR
• Platinum complexes
• Phương pháp nhiễu xạ tia X
• Spectroscopic study
• Tạp chí phân tích Hóa Lý và Sinh học
• Hợp chất arylidenehydrazinyl
• Hợp chất chloroquinoline
• Hợp chất hydrazinylquinoline
• Hợp chất cichloroquinoline
• Antimicrobial activity
• Fly ash
• Waterproofing admixture
• Additive compounds
• Hydraulic structures
• Vibration resistance
• Dimensional stability
• Emission and Function
• Volatile Organic
• Compounds in Response
• Abiotic Stress
• Epigenetic Chromatin
• Regulators as Mediators
• The transition elements
• Advanced inorganic chemistry
• Inorganic chemistry
• The electronic structures
• Organometallic compounds
• Homogeneous catalytic reactions
• Transition matal complexes
• Quinary compounds
• Curie temperature
• Density of states
• Strontium titanate
• Band shifting
• Advanced materials and devices
• Aspidistra letreae
• Chemical constituents
• Cytotoxicity of Aspidistra letreae
• Evaluating cytotoxic activity
• Chemical structures of isolated compounds 1–5