TAILIEUCHUNG - Lecture Organic chemistry - Chapter 8: Alcohols

Lecture Organic chemistry - Chapter 8: Alcohols. The main contents of this chapter include all of the following: Ethanol, cyclic alcohols are called cycloalkanols, physical properties, hydrogen bonding, synthesis of alcohols R-OH,.and other contents. | O Chapter 8: Alcohols R OH H H O CH3 CH3 δ+ O H CH3 δ+ δ+ δ+ δ+ δ+ δ-- δ-- δ-- Water An alcohol An ether Ethanol Industrial Building Block, Fuel Beverage Ethanol plant in West Burlington, Iowa Abuse Initial dose causes euphoria, but alcohol is a general CNS active depressant drug. Macbeth: Act 2, Scene 3, Page 2 MACDUFF . It provokes the desire, but it takes away the performance. 8/11/2015 © University of California 4 Absorption: 20% stomach, 80% gastrointestinal. Food slows it, but what is in, stays in Distribution through the body and brain is fast. Intravenous can be lethal: sudden depression of the respiratory system, brain centers. Excretion: Lungs Alcoholic breath; 5% in urine. Metabolism: Zero order in ROH! Linear with time; 10 mL/h (cocktail/hour); by oxidation: CH3CH2OH CH3CH CO2 Poisonous Second step is prevented by antabuse (disulfiram): O Enzyme Enzyme Common misconceptions: 1. Not a stimulant 2. Doesn’t warm you 3. Doesn’t help your sleep 4. Not an aphrodisiac 1. Find

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