TAILIEUCHUNG - Biofunctionalization of gold nanoshells monitored by surphase plasmon resonance
The GNSs were also attached with biomolecules. The plasmon resonance wavelengths of this GNSs were tunable from visible to near infrared. The attachment process of biomolecules onto the GNSs surfaces was controlled by measuring both their SPR spectra and their zeta potentials. | Vietnam Journal of Science and Technology 56 (5) (2018) 604-611 DOI: BIOFUNCTIONALIZATION OF GOLD NANOSHELLS MONITORED BY SURPHASE PLASMON RESONANCE Nghiem Thi Ha Lien1, *, Do Thi Hue1, 2, Nguyen Thi My An1, 2, Do Quang Hoa1, Nguyen Trong Nghia1, Tran Hong Nhung1 1 Institute of Physics, VAST, 18 Hoang Quoc Viet, Cau Giay District, Ha Noi Graduate University of Science and Technology, VAST, 18 Hoang Quoc Viet, Cau Giay, Ha Noi 2 * Email: halien@ Received: 7 March 2018; Accepted for publication: 24 July 2018 Abstract. Gold nanoshells (GNSs) were grown on monodispersed and aminopropyltriethoxysilane (APTES) functionalized silica nanoparticles (NPs) cores with varying sizes ranging from 60-180 nm, which were prepared by Stober route. Gold shells were deposited onto the surface of silica NPs by using tetrakis(hydroxymethyl) phosphonium chloride (THPC) and an electroless gold plating method. The coverage of the gold nanoshells on the surfaces of the silica NPs was evaluated using surface plasmon resonance (SPR) spectra and scanning electron microscope (SEM). The GNSs were also attached with biomolecules. The plasmon resonance wavelengths of this GNSs were tunable from visible to near infrared. The attachment process of biomolecules onto the GNSs surfaces was controlled by measuring both their SPR spectra and their zeta potentials. Keywords: gold nanoshells, surface plasmon resonance, zeta potential. Classification numbers: ; ; 1. INTRODUCTION Gold nanoshells (GNSs) nanoparticles (NPs) consist of a spherical dielectric core coated with a concentric layer of gold [1]. Due to large extinction cross sections of GNSs between 7001200 nm, it is possible to use them in biological applications such as hyperthermia agents, contrast agents biological imaging, controlled drug release, bioprobes in cell and tissue analysis, and for studying biological processes at the nanoscale [2, 3, 4, 5]. A critical factor limiting
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