TAILIEUCHUNG - Lecture Microbiology - Chapter 7: Microbial genetics

Lecture Microbiology - Chapter 7: Microbial genetics. This chapter presents the following content: Heredity, genetic information storage, DNA structure, DNA concepts, information transfer - gene expression, DNA replication, gene representation,. | MICROBIAL GENETICS CHAPTER 7 Copyright © 2012 John Wiley & Sons, Inc. All rights reserved. Heredity Diversity in the gene pool is vital Eukaryotes – Mating partners – Random chromosome alignment during Meiosis I – Homologous chromatid recombination events Prokaryotes – Mutation/ rapid reproduction rates – Lateral gene transfer () Copyright © 2012 John Wiley & Sons, Inc. All rights reserved. Genetic Information Storage Chromosomal sizes – E. coli 4 x 106 bp – H. sapiens 3 x 109 bp Microbial gene size ~1000bp Gene composition - CG rich Copyright © 2012 John Wiley & Sons, Inc. All rights reserved. DNA Structure Double stranded Helical Sugar-phosphate backbone – 5’ to 3’ orientation Base pairs – A-T – C-G Copyright © 2012 John Wiley & Sons, Inc. All rights reserved. DNA Concepts Genes – Functional unit encoding a protein or RNA product – Often determine a single characteristic – Units are located at fixed loci along the chromosome Alleles – Variations in the base sequences of a gene – Their diversity expands the gene pool Mutations – Alterations in gene sequence which create new alleles – Many chemical and physical causes 5 Copyright © 2012 John Wiley & Sons, Inc. All rights .

• Sinh học
• Lecture Microbiology
• Roles of microbes
• Biological research
• Microbial genetics
• Genetic information storage
• DNA structure
• DNA concepts
• Environmental microbiology
• Energy flow
• Biogeochemical cycles
• Applied microbiology
• Microbes found in food
• Mesophilic canned spoilage
• Biological research uses microbes
• Microbial abundance
• Prokaryotic microbes
• Fundamentals of chemistry
• Atomic structure
• Chemical building blocks
• Metric units
• Light properties
• Compound light microscopy
• Characteristics of prokaryotic
• Eukaryotic cells
• Cellular characteristics
• Prokaryotic cells
• Microbial metabolism
• Energy capture
• Enzymes control metabolic pathways
• Culturing of bacteria
• Cell division
• Bacterial growth curve
• Counting large populations
• Gene transfer
• Genetic engineering
• Plasmid types
• Taxonomic heirarchy
• Taxonomic keys
• Kingdom protista
• Infectious properties
• Virus classification
• Unique RNA virus cycle
• Eukaryotic microorganisms
• Parasite evasion strategies
• Plant like protozoan phyla
• Aseptic principles
• Controlling microbial growth
• Chemical antimicrobials
• Antimicrobial therapy
• Antimicrobial drug properties
• Drug target sites
• Disease processes
• Symbiotic relationships
• Host invasion
• Nosocomial infections
• Infectious disease spread
• Epidemiological terms
• Innate host defenses
• Innate defense
• Cellular defenses
• Adaptive immunity
• Antigen characteristics
• Immune system properties
• Immune disorders
• Immunological tests precipitin
• immunodiffusion plates
• Mucous membranes
• Bacterial skin diseases
• Staphylococcus aureus
• Gastrointestinal diseases
• Bacterial oral cavity disease
• Bacterial gastrointestinal intoxications
• Systemic diseases
• Bacterial septicemias
• Streptococcal diseases
• Nervous system
• Bacterial diseases
• Bacterial meningitis
• Medical assisting
• Clinical procedures
• Administrative medical assisting
• Clinical medical assisting
• Introduction to microbiology
• Bacterial classification