TAILIEUCHUNG - Ebook Fundamentals of organic chemistry (7th edition): Part 2

(BQ) Part 2 book "Fundamentals of organic chemistry" has contents: Carbonyl alpha substitution reactions and condensation reactions, structure determination, the organic chemistry of metabolic pathways; biomolecules - lipids and nucleic acids; biomolecules - amino acids, peptides, and proteins,.and other contents. | CHAPTER 9. U sed 200 Ima Shu ge co tte pyr rsto igh ck. t Ar com iy, The burning sensation produced by touching or eating chili peppers is due to capsaicin, a carboxylic acid derivative called an amide. und er l ice nse fro m 1 0 Carboxylic Acids and Derivatives: Nucleophilic Acyl Substitution Reactions Naming Carboxylic Acids and Derivatives Occurrence and Properties of Carboxylic Acids and Derivatives Acidity of Carboxylic Acids Synthesis of Carboxylic Acids Nucleophilic Acyl Substitution Reactions Carboxylic Acids and Their Reactions Acid Halides and Their Reactions Acid Anhydrides and Their Reactions Esters and Their Reactions Amides and Their Reactions Nitriles and Their Reactions Biological Carboxylic Acid Derivatives: Thioesters and Acyl Phosphates Polymers from Carbonyl Compounds: Polyamides and Polyesters Interlude—␤-Lactam Antibiotics Carboxylic acids and their derivatives are the most abundant of all organic compounds, both in the laboratory and in living organisms. Although there are many different kinds of carboxylic acid derivatives, we’ll be concerned only with some of the most common ones: acid halides, acid anhydrides, esters, amides, and related compounds called nitriles. In addition, acyl phosphates and thioesters are acid derivatives of particular importance in numerous biological processes. The common structural feature of all these compounds is that they contain an acyl group bonded to an electronegative atom or substituent that can act as a leaving group in substitution reactions. 325 326 C H A P T E R 10

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