TAILIEUCHUNG - One new compound from Borreria alata (Aubl.) DC (Rubiaceae) in Vietnam
In this paper, we present the chemical structures of four compounds isolated from Borreria alata, collected at Di Linh district, Lam Dong province, Vietnam. 3β, 6β, 23-trihydroxyurs-12-en-28-oic acid, sodium deacetylasperulosidate, 7β-hydroxy-11-methylforsythide loganate, | TAÏP CHÍ PHAÙT TRIEÅN KH&CN, TAÄP 19, SOÁ T1 - 2016 One new compound from Borreria alata (Aubl.) DC (Rubiaceae) in Vietnam To Cam Loan An Giang University Pham Nguyen Kim Tuyen Sai Gon University Nguyen Kim Phi Phung University of Science, VNU-HCM (Received on July 09 th 2015, accepted on March 29 th 2016) ABSTRACT Borreria is a genus of Rubiaceae widespread in 12-en-28-oic acid (1), sodium deacetylasperulosidate tropical and subtropical America, Africa, Asia, and (2), 7β-hydroxy-11-methylforsythide (3) and sodium Europe. Studies have confirmed that extracts as well loganate (4). Among them, three compounds (1), (2), as some isolated compounds of species of Borreria (3) were known for the first time in Borreria genus to genus possess diverse biological activities, including our best knowledge and (4) is a new compound. The anti-inflammatory, antitumor, antimicrobial, chemical structures of these compounds antioxidant, anti-ulcer In this paper, we present the wereelucidated by analysis of 1D and 2D NMR and chemical structures of four compounds isolated from HR-MS spectroscopic data, as well as by comparison with those reported in the literature. Borreria alata, collected at Di Linh district, Lam Dong province, Vietnam. 3β, 6β, 23-trihydroxyursKeywords: Borreria alata, sodium deacetylasperulosidate, sodium loganate, 3β,6β,23-trihydroxyurs-12-en-28oic acid,7β-hydroxy-11-methylforsythide. INTRODUCTION Borreria alata (Aubl.) DC. (synonym: Spermacoce alata Aubl., B. latifolia K. Schum.) belongs to the Rubiaceae family [2]. In Nepal, the roots juice of Borreria alata is used to treat malaria [3]. There was only one paper that reported the isolation of eight compounds from B. alata growing in Indonesia [4]. In Vietnam, B. alata is a wide weed in coffee gardens and there has not yet been chemically studied. Because phytochemicals depends on phenotypic and genotypic factors, the aim of this study was to investigate the chemical constituents of Borreria alata .
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