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NO is a gaseous molecule, synthesized by NO synthase (NOS), an enzyme that catalyses the oxidation of L-arginine to NO and L-citrulline. At least two types of NOS can be reported, constitutive NOS (cNOS) and inducible NOS (iNOS) (168) . cNOS is produced by many cells in the upper and lower respiratory system, such as parasympathetic vasodilator nerves, endothelial cells and ciliated mucosa cells (169) . iNOS is described in epithelium, macrophages, fibroblasts, neutrophils, endothelium and vascular smooth muscle, and is activated by proinflammatory cytokines and endotoxins (168, 170, 171) . NO is involved in many physiological and pathological processes in human, by. | Acute and Chronic Sinusitis A Practical Guide for Diagnosis and Treatment 1 Presentation Facts File size approximately 2013 KB Number of slides 81 Evidence-Based CME Web site addresses for all EB recommendations are available near the end of this presentation These slides were prepared by the AAFP and content should not be modified in any way. If content is changed it is the user s responsibility to remove both the AAFP and the CME logos. Instructions to remove logos from menu select VIEW MASTER SLIDE MASTER select the logos and delete to return to the original slide view select VIEW SLIDE lU Ali Ề . 0031003 2 Acknowledgments This is a presentation of the American Academy of Family Physicians supported by an educational grant from Aventis Pharmaceuticals U.- Xr The AAFP gratefully acknowledges HaroldH. Hedges III M.D. and Susan M. Pollart M.D. for developing the content for the AAFP and Harold H. Hedges III M.D. for providing the photo images included in this slide presentation.
