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I thank the many governments, international and non-governmental organizations, companies, foundations, constituency groups and advocates who have contributed to the development of this global strategy. this is a first step. It is in all our hands to make a concrete difference as a result of this plan. I call on everyone to play their part. success will come when we focus our attention and resources on people, not their illnesses; on health, not disease. with the right policies, adequate and fairly distributed funding, and a relentless resolve to deliver to those who need it most – we can and will. | INCIDENCE OF CONGENITAL HEART DISEASE AMONG HOSPITAL LIVE BIRTHS IN INDIA A. Khalil R. Aggarwal S. Thirupuram R. Arora ABSTRACT Ten thousand nine hundred and sixty four consecutive live births weighing more than 500 g and more than 28 weeks of gestation were subjected to a thorough clinical examination within 24 h of birth. Those suspected of having congenital heart disease CHD were followed up every 4-6 weeks for a period of 6 to 18 months mean 9.75 months . Forty three of 10 964 infants had CHD i.e. 3.9 1000 live births. Incidence of CHD was higher in pre-terms as compared to full term live births 22.69 vs 2.36 1000 live births . Diagnosis was confirmed by echocardiography including 2D Doppler and color flow imaging. Twenty eight per cent of the infants with CHD had other associated somatic anomalies Down s syndrome being the commonest 9.3 . Patent ductus arteriosus 41.9 and ventricular septal defects VSD 34.9 were the commonest lesions with an incidence of 1.6 and 1.4 1000 live births respectively. Incidence of PDA was higher probably because of larger number of pre-term deliveries. During follow up of 6-18 months 34.9 of the infants with CHD died. The diagnosis of CHD was confirmed at autopsy in 20 of the deaths. Key words Congenital heart disease Prematurity Mortality. The incidence of congenital heart disease CHD depends upon various factors the nature of the sample all live births or all births the source of information birth or death certificates or on the spot examination by a pediatric cardiologist. The incidence is higher if early spontaneous abortions are also included. Recent studies have reported incidence of CHD to range between 4.05 to 10.2 1000 live births. Earlier reported incidence of CHD of 3-5 1000 live births was low because of inadequate diagnostic techniques and availability of ineffective surgical therapy l . This prospective study was conducted to ascertain the incidence of CHD in live births with subsequent confirmation of diagnosis by .
