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Tuyển tập các báo cáo nghiên cứu về bệnh học thý y được đăng trên tạp chí Acta Veterinaria Scandinavica cung cấp cho các bạn kiến thức về bệnh thú yđề tài: Factors associated with the success of rabies vaccination of dogs in Sweden. | Berndtsson et al. Acta Veterinaria Scandinavica 2011 53 22 http www.actavetscand.eom content 53 1 22 AVS ACTAVETERINARIA Sco dmov cc a SCANDINAVICA RESEARCH Open Access Factors associated with the success of rabies vaccination of dogs in Sweden Louise T Berndtsson Ann-Kristin J Nyman Esteban Rivera Berndt Klingeborn Abstract Background United Kingdom Ireland Malta and Sweden maintain their national provisions for a transitional period regarding rules concerning rabies vaccination and individual serological test for rabies neutralizing antibodies. The purpose of vaccinating dogs against rabies is to establish pre-exposure immunity and protect individual animals from contracting rabies. The aim of the study was to investigate factors associated with reaching the internationally accepted threshold antibody titre of 0.5 IU mL after rabies vaccination of dogs. Methods The study was a prospective single cohort study including 6 789 samples from Swedish dogs vaccinated with commercially available vaccines in Sweden and the dog s antibody responses were determined by the OIE approved FAVN test. Information on potential risk factors breed age gender date of vaccination vaccine label and the number of vaccinations was collected for each dog. Associations between the dependent variable serological response 0.5 IU mL or 0.5 IU mL and each of the potential risk factors were investigated using logistic regression analysis. Results Of 6 789 vaccinated dogs 6 241 91.9 had an approved test result of 0.5 IU mL. The results of the multivariable logistic regression analysis showed that vaccinating with vaccine B reduced the risk of having antibody titres of 0.5 IU mL by 0.2 times compared with vaccination using vaccine A. Breed size was found significant as an interaction with number of vaccinations and age at vaccination as an interaction with day of antibody testing after last vaccination. In summary larger breeds were at higher risk of having antibody titres of 0.5 IU mL but if .