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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài:"Tissue fibrocytes in patients with mild asthma: A possible link to thickness of reticular basement membrane. | Respiratory Research BioMed Central Research Open Access Tissue fibrocytes in patients with mild asthma A possible link to thickness of reticular basement membrane Kristian Nihlberg 1 Kristoffer Larsen1 Anna Hultgârdh-Nilsson1 Anders Malmstrom1 Leif Bjermer2 and Gunilla Westergren-Thorsson 1 Address Department of Experimental Medical Science Section for Vascular and Airway Research Lund University BMC C13 S-221 84 Lund Sweden and 2Department of Respiratory Medicine and Allergology Lund University Hospital S-221 85 Lund Sweden Email Kristian Nihlberg - kristian.nihlberg@med.lu.se Kristoffer Larsen - kristoffer.larsen@med.lu.se Anna Hultgârdh- Nilsson - Anna.Hultgardh@med.lu.se Anders Malmstrom - anders.malmstrom@med.lu.se Leif Bjermer - leif.bjermer@med.lu.se Gunilla Westergren-Thorsson - gunilla.westergren-thorsson@med.lu.se Corresponding authors Published 29 March 2006 Received 19 September 2005 Respiratory Research2006 7 50 doi 10.1186 1465-9921 -7-50 Accepted 29 March 2006 This article is available from http respiratory-research.cOm content 7 1 50 2006Nihlberg et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Myofibroblasts proposed as being derived from circulating fibrocytes are considered to be important cells in thickening of the basement membrane in patients with asthma. We have studied the correlation of tissue fibrocyte levels to basement membrane thickness and the presence of fibrocytes in bronchoalveolar lavage fluid BALF in steroid-naive patients with mild asthma and controls. Methods Patients with mild asthma n 9 were recruited and divided into two categories based on whether or not fibroblast-like cells could be established from BALF. Non-asthmatic healthy subjects n 5 were used as .
