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Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí hóa học đề tài :Using Chinese Version of MYMOP in Chinese Medicine Evaluation: Validity, Responsiveness and Minimally Important Change | Chung et al. Health and Quality of Life Outcomes 2010 8 111 http www.hqlo.eom content 8 1 111 HEALTH AND QUALITY of life outcomes RESEARCH Open Access Using Chinese Version of MYMOP in Chinese Medicine Evaluation Validity Responsiveness and Minimally Important Change 1 2 1 2 3 3 Vincent CH Chung Vivian CW Wong Chun Hong Lau Henny Hui Tat Hing Lam Lin Xiao Zhong Samuel YS Wong 1 Sian M Griffiths1 Abstract Background Measure Yourself Medical Outcome Profile MYMOP is a patient generated outcome instrument applicable in the evaluation of both allopathic and complementary medicine treatment. This study aims to adapt MYMOP into Chinese and to assess its validity responsiveness and minimally important change values in a sample of patients using Chinese medicine CM services. Methods A Chinese version of MYMOP CMYMOP is developed by forward-backward-forward translation strategy expert panel assessment and pilot testing amongst patients. 272 patients aged 18 or above with subjective symptoms in the past 2 weeks were recruited at a CM clinic and were invited to complete a set of questionnaire containing CMYMOP and SF-36. Follow ups were performed at 2nd and 4th week after consultation using the same set of questionnaire plus a global rating of change question. Criterion validity of CMYMOP was assessed by its correlation with SF-36 at baseline and responsiveness was evaluated by calculating the Cohen effect size ES of change at two follow ups. Minimally important difference MID values were estimated via anchor based method while minimally detectable difference MDC figures were calculated by distribution based method. Results Criterion validity of CMYMOP was demonstrated by negative correlation between CMYMOP Profile scores and all SF-36 domain and summary scores at baseline. For responsiveness between baseline and 4th week follow up ES of CMYMOP Symptom 1 Activity and Profile reached the moderate change threshold ES 0.5 while Symptom 2 and Wellbeing reached the weak change .