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Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí hóa học đề tài : Quality of life of adolescents with cancer: family risks and resources | Barakat et al. Health and Quality of Life Outcomes 2010 8 63 http www.hqlo.eom content 8 1 63 I HEALTH AND QUALITY OF LIFE OUTCOMES RESEARCH Open Access Quality of life of adolescents with cancer family risks and resources Lamia P Barakat 1 2 Paige L Marmer3 and Lisa A Schwartz4 Abstract Purpose The goal of this study was to evaluate the relative contribution of treatment intensity family sociodemographic risk and family resources to health-related quality of life QOL of 102 adolescents in treatment for cancer. Methods Adolescents and parents completed self-report measures of teen QOL family functioning and parent-child bonding. Based on parent report of family sociodemographic variables an additive risk index was computed. A pediatric oncologist rated treatment intensity. Results Simultaneous regression analyses demonstrated the significant contribution of roles in family functioning and quality of parent-child relationship to prediction of psychosocial QOL parent and teen-reported as well as parent-reported teen physical QOL over and above the contribution of treatment intensity. Family sociodemographic risk did not contribute to QOL in these regression analyses. In additional analyses specific diagnosis types of treatment and individual sociodemographic risk variables were not associated with QOL. Parent and teen ratings of family functioning and quality of life were concordant. Conclusions Family functioning including quality of parent-child relationship are central and potentially modifiable resistance factors in teen QOL while under treatment for cancer. Even more important than relying on diagnosis or treatment screening for roles and relationships early in treatment may be an important aspect of determining risk for poor QOL outcomes. Background Research examining the physical social and emotional consequences of pediatric cancer and its treatment highlights the significant impact on health-related quality of life QOL 1-3 . The preponderance of research on
