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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Distinct synovial immunopathology in Behçet disease and psoriatic arthritis. | Available online http arthritis-research.eom content 11 1 R17 Research article Distinct synovial immunopathology in Behẹet disease and psoriatic arthritis Juan D Canete1 Raquel Celis1 Troy Noordenbos2 Conchita Moll1 Jose A Gomez-Puerta1 Pilar Pizcueta3 Antonio Palacin4 Paul PTak2 Raimon Sanmartí1 and Dominique Baeten2 Arthritis Unit Department of Rheumatology Hospital Clinic de Barcelona and IDIBAPS Villaroel 170 Barcelona 08036 Spain 2Clinical Immunology and Rheumatology Academic Medical Center University of Amsterdam Meibergdreef 9 Amsterdam 1105 AZ The Netherlands 3Immunology Unit Department of Cell Biology and Pathology Calle Casanova 143 Universidad de Barcelona 08036 Spain 4Department of Pathology Hospital Clinic de Barcelona Villaroel 170 Barcelona 08036 Spain Corresponding author Dominique Baeten D.L.Baeten@amc.uva.nl Received 22 Sep 2008 Revisions requested 10 Nov 2008 Revisions received 29 Dec 2008 Accepted 6 Feb 2009 Published 6 Feb 2009 Arthritis Research Therapy 2009 11 R17 doi 10.1186 ar2608 This article is online at http arthritis-research.com content 11 1 R17 2009 Canete et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction The aim of the study was to investigate synovial immunopathology differences between early Behẹet disease BD and psoriatic arthritis PsA . Methods Needle arthroscopy of an inflamed knee joint was performed in patients with early untreated BD n 8 and PsA n 9 . Synovial fluid SF was collected for cytokines perforin and granzyme analysis. Eight synovial biopsies per patient were obtained for immunohistochemical analysis of the cellular infiltrate T cells natural killer cells macrophages B cells plasma cells mast cells and neutrophils blood vessels as well .
