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Tuyển tập các báo cáo nghiên cứu khoa học ngành y học tạp chí Medical Sciences dành cho các bạn sinh viên ngành y tham khảo đề tài: Hepatitis B Virus (HBV) and Hepatitis C Virus (HCV) Dual Infection. | Int. J. Med. Sci. 2006 3 57 Review International Journal of Medical Sciences ISSN 1449-1907 www.medsci.org 2006 3 2 57-62 2006 Ivyspring International Publisher. All rights reserved Hepatitis B Virus HBV and Hepatitis C Virus HCV Dual Infection Zhihua Liu and Jinlin Hou Department of Infectious Diseases and Hepatology Unit Nanfang Hospital Southern Medical University Guangzhou China Corresponding address Jinlin Hou M.D Hepatology Unit and Dept. of Infectious Diseases Nanfang Hospital Guangzhou 510515 China. email jlhou@fimmu.com Tel 86-20-61641941 Fax 86-20-87714940 Received 2005.12.30 Accepted 2006.03.15 Published 2006.04.01 Hepatitis B virus HBV and hepatitis C virus HCV infections account for a substantial proportion of liver diseases worldwide. Because the two hepatotropic viruses share same modes of transmission coinfection with the two viruses is not uncommon especially in areas with a high prevalence of HBV infection and among people at high risk for parenteral infection. Patients with dual HBV and HCV infection have more severe liver disease and are at an increased risk for progression to hepatocellular carcinoma HCC . Treatment of viral hepatitis due to dual HBV HCV infection represents a challenge. Key words Hepatitis B virus hepatitis C virus coinfection epidemiology hepatocellular carcinoma HCC 1. Introduction Approximately 350 million people are infected with HBV worldwide and the World Health Organization WHO estimates that approximately 170 million people are infected with HCV. HBV and HCV infection account for a substantial proportion of liver diseases worldwide. Because the two hepatotropic viruses share same modes of transmission coinfection with the two viruses is not uncommon especially in areas with a high prevalence of HBV infection and among people at high risk for parenteral infection. The exact number of patients infected with both HCV and HBV is unknown. 2. Epidemiology Dual infection with HBV and HCV is not uncommon in geographic areas .
