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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Daily illumination exposure and melatonin: influence of ophthalmic dysfunction and sleep duration. | BioMed Central Journal of Circadian Rhythms Research Open Access Daily illumination exposure and melatonin influence of ophthalmic dysfunction and sleep duration Girardin Jean-Louis 1 2 3 Daniel F Kripke4 Jeffrey A Elliott4 Ferdinand Zizi1 2 Arthur H Wolintz1 2 and Douglas R Lazzaro1 Address Department of Psychiatry and Ophthalmology SUNY Downstate Medical Center New York NY 2Brooklyn Research Foundation on Minority Health KJMC New York NY 3Department of Psychiatry Maimonides Medical Center New York NY and 4Department of Psychiatry University of California San Diego CA Email Girardin Jean-Louis - gjean-louis@downstate.edu Daniel F Kripke - dkripke@ucsd.edu Jeffrey A Elliott - jelliott@ucsd.edu Ferdinand Zizi - fzizi@downstate.edu Arthur H Wolintz - awolintz@downstate.edu Douglas R Lazzaro - dlazzaro@downstate.edu Corresponding author Published 01 December 2005 Received 13 October 2005 __ _ D.__AAAC . A I O - .A - - o I - I- Accepted 01 December 2005 Journal of Circadian Rhythms 2005 3 13 doi l0.ll86 1740-3391-3-13 This article is available from http www.jcircadianrhythms.cOm content 3 1 1 3 2005 Jean-Louis et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Ocular pathology lessens light s efficacy to maintain optimal circadian entrainment. We examined whether ophthalmic dysfunction explains unique variance in melatonin excretion of older adults over and above the variance explained by daily illumination medical and sociodemographic factors. We also examined whether ophthalmic dysfunction influences relationships between ambient illumination and melatonin. Methods Thirty older adults mean age 69 years Blacks 42 and Whites 58 of both genders participated in the study. Demographic and health data were
