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Bên trong khu vực (paracortex hoặc sâu vỏ não). Với mô bạch huyết lan tỏa bao gồm các tế bào lympho T Xoang trong vỏ não. Loose mạng của các đại thực bào và các sợi lưới thông qua đó các bạch huyết percolates - | 140 Digital Histology Inner zone paracortex or deep cortex . Filled with diffuse lymphoid tissue composed of T lymphocytes Sinuses in cortex. Loose network of macrophages and reticular fibers through which lymph percolates - Subcapsular sinus lies immediately beneath the capsule and receives incoming lymph fluid from afferent lymphatic vessels that enter through the capsule. - Intermediate sinuses. Lie adjacent to the trabeculae. Receive lymph from the subcapsular sinus and continue as medullary sinuses Medulla. Composed of Medullary cords of B lymphocytes that extend from the inner cortex into the medulla Medullary sinuses. Continuations of the intermediate sinuses in the cortex. Lymph flows from medullary sinuses into the efferent lymph vessels that exit at the hilum of the node. Blood supply. Small arteries enter at the hilum to supply a capillary plexus in the outer cortex. The capillaries anastomose to form HEVs in the paracortex and small veins that exit at the hilum. Filter and provide immune surveillance for lymph Spleen Encapsulated intraperitoneal organ located in upper left quadrant of the abdominal cavity Structure Capsule surrounds organ sending trabeculae into the spleen. Larger blood vessels enter through the trabeculae. Subdivisions White pulp appears white in fresh specimens and is composed of - Periarterial lymphoid sheath PALS . A sleeve of T lymphocytes that surrounds a central arteriole as soon as it exits from a trabecula - Lymphoid nodules composed of B lymphocytes are randomly located along and embedded in the PALS. Red pulp appears red in fresh specimens because of the abundant venous sinuses it possesses. - Splenic cords of Billroth . Cords of lymphocytes T and B macrophages plasma cells and other lymphoid cells suspended in a reticular connective tissue stroma. Surrounded by 14. Lymphoid System 141 - Splenic sinuses. Venous sinuses separating splenic cords. These sinuses are lined by endothelial cells and surrounded by reticular fibers. .
