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Unlike the studies described above, the Age-Related Eye Disease Study (AREDS), led by the National Eye Institute and cosponsored by other components of NIH, including NCCAM, found a beneficial effect of antioxidant supplements. This study showed that a combination of antioxidants (vitamin C, vitamin E, and beta-carotene) and zinc reduced the risk of developing the advanced stage of age-related macular degeneration by 25 percent in people who had the intermediate stage of this disease or who had the advanced stage in only one eye. Antioxidant supplements used alone reduced the risk by about 17 percent. In the same study, however,. | _. _ _. _ Ểẩiằ World Health The Global Organization Occupational Health Network OHNET ISSUE No. 11 - 2006 GOHNET NEWSLETTER PREVENTION OF OCCUPATIONAL CANCER A variety of occupational risks is known to cause cancer. Every year more than seven million people die of cancer. Forty percent of these cases could be prevented which means that one in every ten cancer deaths is preventable through interventions targeted on exposure in the working environment. The articles in this issue of GOHNET highlight some aspects of the problem and the prevention of occupational cancer. The articles draw your attention to the large number of workers exposed to specific carcinogens such as asbestos UV radiation tobacco smoke as well as to those workers engaged in occupations and industries where there is an increased risk of cancer for example the chemical and rubber industry. The articles also deal with the serious problem of how the vital organs of workers are affected such as the bladder lung skin and others. We hope that you will enjoy your reading and at the same time invite you to contribute to the next GOHNET Newsletter on the topic Elimination of Silicosis . References for articles are posted on the Occupational Health website at www.who.int occupational_health publications newsletter en index.html. Evelyn Kortum Editor Kati Bozsoki Co-Editor World Health Organization Occupational Environmental Health Programme Department of Protection of the Human Environment 20 Avenue Appia CH - 1211 Geneva 27 Fax 41.22.791 13 83 ochmail@who.int www.who.int occupational_health Occupational Cancer Ivan D. Ivanov Occupational Health Programme WHO Geneva Switzerland ivanovi@who. int and Kurt Straif International Agency for Research on Cancer Lyon France IARC straif@iarc.fr Definition of the problem Occupational cancer accounts for about 4 to 20 of the cancer cases. It affects certain groups of the society much more than others. Furthermore occupational risks for cancer are taken involuntarily as