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Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí hóa học quốc tế đề tài :The impact of itch symptoms in psoriasis: results from physician interviews and patient focus groups | Health and Quality of Life Outcomes BioMed Central Open Access The impact of itch symptoms in psoriasis results from physician interviews and patient focus groups Denise Globe 1 Martha S Bayliss2 and David J Harrison1 Address 1Amgen Inc One Amgen Center Drive Thousand Oaks CA 91320 USA and 2Mapi Values 3rd Floor 133 Portland Street Boston MA 02114 USA Email Denise Globe - dglobe@amgen.com Martha S Bayliss - martha.bayliss@mapivalues.com David J Harrison - davidh01@amgen.com Corresponding author Published 6 July 2009 Received 19 December 2008 Health and Quality of Life Outcomes 2009 7 62 doi 10.1186 1477-7525-7-62 Accepted 6 July 2009 This article is available from http www.hqlo.com content 7 1 62 2009 Globe et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.Org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background The objective of this qualitative study was to better understand the impact of psoriasis symptoms using a 3-part process 1 develop a disease model for psoriasis to identify the most important concepts relevant to psoriasis patients 2 conduct interviews with dermatologists to identify key areas of clinical concern and 3 explore psoriasis patients perceptions of the impact of psoriasis. Methods A disease model was developed from a review of the published literature and later revised based on the findings of clinician interviews and patient focus groups. To confirm the clinical relevance of the concepts identified in the disease model 5 dermatologists were selected and interviewed one-on-one. They were asked to rate major psoriasis symptoms according to importance and bothersomeness level to patients on separate scales of 1 to 10. Results of clinician interviews were used to develop interview guides for patient focus groups. To identify important .