tailieuchung - Genetic background modifies phenotypic and transcriptional responses in a C. elegans model of α-synuclein toxicity

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Genetic background modifies phenotypic and transcriptional responses in a C. elegans model of α-synuclein toxicity

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Accumulation of protein aggregates are a major hallmark of progressive neurodegenerative disorders such as Parkinson’s disease and Alzheimer’s disease. Transgenic Caenorhabditis elegans nematodes expressing the human synaptic protein α-synuclein in body wall muscle show inclusions of aggregated protein, which affects similar genetic pathways as in humans. |

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Genetic background modifies phenotypic and transcriptional responses in a C. elegans model of α-synuclein toxicity

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Genetic background modifies phenotypic and transcriptional responses in a C. elegans model of α-synuclein toxicity

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Đang chuẩn bị liên kết để tải về tài liệu: Genetic background modifies phenotypic and transcriptional responses in a C. elegans model of α-synuclein toxicity