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Mannan oligosaccharide requires functional ETC and TLR for biological radiation protection to normal cells

Low LET Ionizing radiation is known to alter intracellular redox balance by inducing free radical generation, which may cause oxidative modification of various cellular biomolecules. The extent of biomoleculemodifications/ damages and changes in vital processes (viz. cellular homeostasis, inter−/intra-cellular signaling, mitochondrial physiology/dynamics antioxidant defence systems) are crucial which in turn determine fate of cells. |