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This study aims to employ highly efficient ultrasound-assisted extraction of tamanu oil from seed kernel. Response surface methodology (RSM) with Box-Hunter design was used to investigate the simultaneous effects of multi-factors encompassing extraction time, temperature, and solvent-to-material ratio. The optimum combination of those factors was then determined to ensure optimum extraction efficiencies [12, 13]. The extracted oil was evaluated in terms of physicochemical indexes, composition, and wound healing activity. |