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Human fungal infections are on the rise. Fungi causing skin infections are common but invasive fungi which are less known appear pathogenic and deadly. Environment, immunity and individual risk factors contribute for its susceptibility. Some of them can be fatal, if not diagnosed early and treated. Advances in molecular techniques help in early diagnosis. New modality of treatment such as antifungal peptides, fungal vaccines are in the pipeline. Improper and “Over the counter” medication must be avoided for the complete cure. | Newer aspects of diagnosis and treatment of human fungal infection