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A study was conducted to compare efficacy of PGF2α and PGF2α fortified with bypass fat, minerals and vitamins for treatment of silent oestrus in crossbred cows based on oestrus induction response and post treatment conception rate. The study revealed that double intramuscular injection of PGF2α at 11 days apart resulted in 100.00 per cent oestrus response rate and 66.66 per cent post treatment conception rate in silent oestrous crossbred cows. Fortification of PGF2α with supportive treatment comprising oral bypass fat, mineral mixture and injectable phosphorus and vitamins also resulted in 100.00 per cent oestrus response and 66.66 per cent conception rate. With supportive treatment alone only 33.33 per cent oestrus response and 33.33 per cent conception rate could be obtained. It could be concluded that fortification of PGF2α with supportive drugs did not improve its efficacy in the management of silent oestrus in crossbred cattle. | Fortification needs of PGF2α with bypass fat, minerals and vitamins for treatment of silent oestrus in crossbred cows