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Brown leaf spot of Rice, caused by Bipolaris oryzae L is one of the major rice diseases occurring in World and Nepal. A field experiment to evaluate the efficacy of different chemical fungicides against brown leaf spot of rice was conducted at the farmer’s field in Galkot municipality ward no.4. The six different fungicides that were compared with control treatment were Propaconazole, Hexaconazole, Teuboconazole, Carbendazim, Mancozeb allocated in Randomized Completely Block Design (RCBD) and replicated for three times. Application of propiconazole showed the lower AUDPC value (415.7) and highest grain yield (4.277 t/ha) followed by Kyoto (464.3) and SAAF (513.7) as compared to control. From this result, it was concluded that propiconazole can be used to reduce the disease severity and for higher economic yield. | Influence of different chemical fungicides against rice brown leaf spot disease caused by Bipolaris Oryzae