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Plasmid induces the production of extra-cellular enzymes called β-lactamases, and also, encoded resistance genes which are often located within genetic elements. This study evaluated the plasmid profile of bacterial isolates cultured from urine samples of HIV seropositive pregnant women that attended antenatal clinic of the Ondo State Specialist hospital, Akure. Plasmid analysis of bacterial isolates was also done by alkaline method. The resistance gene (plasmid) was detected in E. coli and Pseudomonas aeruginosa isolates used. The study concluded that appearance of the resistance genes in some of these bacterial isolates could help the isolates to be multidrug resistant which may lead to a serious public health challenges. | Nội dung Text Plasmid profile of bacteria
