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Turmeric is a spice that has been used extensively used in the different food sectors as a flavoring and coloring agent, in almost every cellular biological event, process includes in the gene expression, signaling and regulation. The bioactive polyphenol present in the turmeric is curcumin, which plays an important role in the anti-inflammatory, anti-oxidant, anticarcinogenic, anti-invasive as a mediator of chemo resistance, radio resistance, chemopreventive agent, and as a therapeutic agent in wound healing, dyspepsia,diabetes and cardiovascular ailments, rheumatism, body ache, hepatic disorders, skin diseases, intestinal worms, constipation, diarrhoea, intermittent fevers, urinarydischarges, inflammations, biliousness, leukoderma, amenorrhea, and colic. | EXCELLENT PUBLISHERS International Journal of Current Microbiology and Applied Sciences ISSN 2319-7706 Volume 7 Number 02 2018 Journal homepage http www.ijcmas.com Review Article https doi.org 10.20546 ijcmas.2018.702.137 Curcumin and Its Biological Importance A Review Praveen Kumar Dikkala1 and S.D.S.N. Shirisha2 1Professor Jayashankar Telangana State Agricultural University Hyderabad-500030 Telangana India 2APAC LAMfarm Andhra Pradesh Agricultural University Guntur Andhra Pradesh India Corresponding author ABSTRACT Keywords Curcumin and Biological Importance Anti-inflammatory Article Info Accepted 10 January 2018 Available Online 10 February 2018 Turmeric is a spice that has been used extensively used in the different food sectors as a flavoring and coloring agent in almost every cellular biological event process includes in the gene expression signaling and regulation. The bioactive polyphenol present in the turmeric is curcumin which plays an important role in the anti-inflammatory anti-oxidant anti-carcinogenic anti-invasive as a mediator of chemo resistance radio resistance chemopreventive agent and as a therapeutic agent in wound healing dyspepsia diabetes and cardiovascular ailments rheumatism body ache hepatic disorders skin diseases intestinal worms constipation diarrhoea intermittent fevers urinarydischarges inflammations biliousness leukoderma amenorrhea and colic. Curcumin has the potential to treat a wide variety of inflammatory diseases including cancer diabetes cardiovascular diseases arthritis Alzheimer s disease andpsoriasis through modulation of numerous molecular targets. With time more and more of its medicinal uses were discovered and today curcumin is associated with a plethora of beneficial effects on human health. Introduction Now a day s many number of plant derivatives such as flavonoids and polyphenols have gained much attention due to their specific biological effects. In these different compounds curcumin has emerged as a bioactive .
